Aciphex (Rabeprazole Sodium) 20mg – Complete Product Guide | EZ Chemist Online Pharmacy
Aciphex 20mg Tablets – Rabeprazole Sodium for Acid Reflux, GERD & Ulcer Relief | Buy Online at EZ Chemist
Aciphex 20mg contains rabeprazole sodium, a proton pump inhibitor (PPI) used to treat GERD, acid reflux, stomach ulcers, and Zollinger-Ellison syndrome. It works by reducing stomach acid production and providing long-lasting relief from heartburn and acid-related damage.
:
Product Name: Aciphex

Generic Name: Rabeprazole Sodium

Strength: 20 mg

Form: Delayed-release Tablets

Pack Size: Available in 14, 28, or 30 tablets

Drug Class: Proton Pump Inhibitor (PPI)

Availability: Prescription-Only Medicine (Rx)

Brand Availability in India: Buy Aciphex 20mg Online – EZ Chemist
Rabeprazole Sodium 20mg
Rabeprazole is a substituted benzimidazole and a PPI (Proton Pump Inhibitor) that selectively and irreversibly blocks gastric H+/K+-ATPase enzyme, thereby suppressing gastric acid secretion.
Generic Names: Rabeprazole

Brand Equivalents: Pariet, Rabicip, Rabemac, Razo, Rabeloc, Rabium

Rabeprazole inhibits the H+/K+-ATPase enzyme (proton pump) in gastric parietal cells. This blocks the final step in acid production, leading to a profound and sustained decrease in gastric acid secretion regardless of the stimulus (e.g., food intake or stress).

A study published in Alimentary Pharmacology & Therapeutics (2002) shows that rabeprazole achieves faster symptom relief and mucosal healing compared to omeprazole and lansoprazole in GERD patients.

Aciphex is used in the treatment of:

Gastroesophageal Reflux Disease (GERD)

Acid Reflux / Heartburn

Peptic Ulcer Disease (PUD)

Zollinger-Ellison Syndrome

Erosive Esophagitis

H. pylori eradication (in combination with antibiotics)

Indication Adult Dose Duration
GERD 20 mg once daily 4–8 weeks
Duodenal Ulcers 20 mg once daily Up to 4 weeks
H. pylori Eradication 20 mg twice daily (with antibiotics) 7–14 days
Zollinger-Ellison Syndrome 60 mg/day (titrate as needed) Individualized

Administration: Swallow whole; do not crush or chew. Take before meals, preferably in the morning.
Pregnancy Category: Category B – Use only if clearly needed

Pediatric Use: Approved for children >12 years (consult paediatrician)

Elderly Use: No dosage adjustment required

Renal/Hepatic Adjustment: Caution in severe hepatic impairment

Safety Information:
Common Side Effects:
Headache

Diarrhea

Constipation

Nausea

Flatulence
Vitamin B12 deficiency (long-term use)

Hypomagnesemia

Clostridium difficile-associated diarrhea

Bone fractures (with chronic use)

Acute interstitial nephritis

Fundic gland polyps
Long-term use warning: Prolonged therapy (>1 year) may increase risk of osteoporosis, B12 deficiency, and kidney disease.

Discontinue immediately if signs of allergic reaction (rash, swelling, breathing difficulty) occur.

Use cautiously in patients with hepatic impairment.

Regular monitoring required for electrolyte levels and renal function in chronic users.

Rabeprazole may interact with:

Clopidogrel: May reduce its antiplatelet effect.

Ketoconazole/itraconazole: Decreased absorption due to reduced gastric acidity.

Warfarin: Possible increase in INR.

Methotrexate: Increased serum levels and toxicity.

HIV Protease Inhibitors (e.g., atazanavir): Reduced efficacy due to acid suppression.

Clinical Backing:
According to The American Journal of Gastroenterology, co-administration of PPIs with clopidogrel should be assessed on an individual risk-benefit basis, especially in patients with cardiovascular disease.
Store at room temperature (15°C–30°C)

Protect from light and moisture

Keep out of reach of children

Frequently Asked Questions (FAQs):
Q1: What is Aciphex used for?
Aciphex is used to treat acid-related conditions such as GERD, stomach ulcers, and erosive esophagitis.

Q2: Is Aciphex safe for long-term use?
Yes, but long-term use requires medical supervision due to potential risks like bone loss and nutrient deficiencies.

Q3: Can I take Aciphex with food?
It is best taken before meals, typically in the morning for optimal effect.

Q4: Can pregnant or breastfeeding women take Aciphex?
Use only if prescribed by a healthcare provider. Animal studies show no risk, but human data is limited.

Q5: How long does Aciphex take to work?
Symptom relief may begin within 1–2 days, but full acid suppression may take up to 4 days.

Q6: Is Aciphex better than omeprazole?
Clinical studies suggest that rabeprazole (Aciphex) offers faster acid suppression and comparable or superior mucosal healing with fewer drug interactions.

Clinical References & Evidence-Based Data:
Mekkel G. et al. – Comparative study on rabeprazole vs omeprazole in GERD (Aliment Pharmacol Ther. 2002)

FDA Prescribing Information – Aciphex (Rabeprazole Sodium)

PubMed Clinical Trials Database – Rabeprazole and Helicobacter pylori eradication

Martindale: The Complete Drug Reference – Rabeprazole entry

Buy Aciphex 20mg Online in India – EZ Chemist Pharmacy
Purchase Aciphex (Rabeprazole Sodium 20mg) online from EZ Chemist with assured quality and delivery. Get reliable treatment for acid reflux and ulcers at competitive pricing with professional support.

Order Aciphex Now – EZ Chemist Online Pharmacy
Aciphex 20mg, Rabeprazole Tablets, Acid Reflux Medicine, GERD Treatment, Ulcer Medicine, Proton Pump Inhibitor, Prescription Acid Reducer, Buy Rabeprazole India, EZ Chemist Pharmacy, Heartburn Relief