Actonel (Risedronate Sodium)
Prepared for: EZ Chemist Online Pharmacy
Reference Product Pair: Blackmores Conceive Well Gold 28 Tablets + 28 Capsules
Actonel Risedronate 35mg tablets, osteoporosis medicine Australia, bisphosphonate bone health supplement, EZ Chemist bone strength treatment

What is Actonel used for?
Actonel is a prescription medication used to treat and prevent osteoporosis in postmenopausal women and patients on corticosteroids. It contains risedronate sodium, a bisphosphonate that works by slowing bone loss and increasing bone density.

Actonel
Generic Name: Risedronate Sodium
Common Strengths: 5 mg (daily), 35 mg (weekly), 150 mg (monthly)
Form: Oral tablets
Packaging: Usually 4 or 12 tablets per pack
Prescription Status: Prescription Only Medicine (Schedule 4 – Australia)
Risedronate Sodium

Other Popular/Common Names:
Risedronate

Actonel EC (enteric-coated formulation)

Osteoporosis prevention tablets

Bisphosphonate bone medication

Bone loss prevention tablets

Risedronate belongs to a class of drugs called bisphosphonates. It works by:

Inhibiting osteoclast activity, the cells responsible for bone breakdown

Preserving bone mineral density (BMD)

Reducing the risk of fractures, particularly in the spine and hip

By binding to bone minerals, Actonel helps maintain bone strength and prevent further deterioration in conditions such as osteoporosis.
Treatment and prevention of postmenopausal osteoporosis

Glucocorticoid-induced osteoporosis

Treatment of Paget’s disease of bone

May also reduce the risk of vertebral and non-vertebral fractures in osteoporotic individuals
Osteoporosis (Postmenopausal):

35 mg once weekly or 5 mg once daily

Glucocorticoid-induced osteoporosis:

5 mg once daily
Paget's Disease:
30 mg once daily for 2 months
Take first thing in the morning, at least 30 minutes before food or drink (except water)

Swallow whole with a full glass of plain water (not mineral water)

Stay upright for at least 30 minutes after taking to prevent oesophageal irritation

Do not chew or crush tablets
Prescription Required: Yes

Pregnancy Category: B3 (not recommended during pregnancy)

Should not be used in pregnancy or while trying to conceive — not compatible with Blackmores Conceive Well Gold
Abdominal pain

Indigestion or heartburn

Diarrhoea or constipation

Muscle or joint pain

Headache

Less Common / Rare:
Oesophagitis

Gastric ulcers

Hypocalcaemia (low calcium)

Jaw osteonecrosis (rare but serious; usually in cancer therapy or poor dental health)

Most side effects can be minimised by following proper administration guidelines.

Warnings & Precautions:
Not recommended for use in pregnancy or during fertility planning (avoid combining with Blackmores Conceive Well Gold)

Ensure adequate calcium and vitamin D intake during treatment
Hypocalcaemia
Severe kidney disease (creatinine clearance <30 mL/min)

Inability to remain upright for 30 minutes

Dental check-up is recommended before starting therapy (risk of jaw osteonecrosis in high-risk groups)
Calcium supplements, antacids, magnesium or iron: Reduce absorption of risedronate — avoid taking within 30–60 minutes

NSAIDs: May increase risk of GI irritation

Thiazide diuretics: Risk of hypercalcaemia (monitor electrolytes)
Therapeutic Class: Anti-osteoporotic agent

Pharmacologic Class: Bisphosphonate

Regulatory Status: Schedule 4 (Prescription Only)

FAQs – Frequently Asked Questions:
Q1. How long should I take Actonel for osteoporosis?
A: Duration varies based on bone mineral density results and fracture risk. Some patients take it for 3–5 years, followed by reassessment or a “drug holiday.”

Q2. Can I take Actonel and Blackmores Conceive Well Gold together?
A: No. Actonel is not suitable during conception or pregnancy. It should be discontinued well before planning pregnancy.

Q3. Is calcium supplementation required with Actonel?
A: Yes. Patients must maintain adequate calcium and vitamin D levels for Actonel to be effective.

Q4. When will I see results from Actonel?
A: Improvements in bone mineral density may take 6 to 12 months. Fracture risk reduction can occur within the first year.

Q5. Can I lie down after taking Actonel?
A: No. You must remain upright for at least 30 minutes to avoid oesophageal irritation or ulcers.

Clinical Studies & Efficacy:
Large-scale trials show that risedronate reduces the incidence of vertebral fractures by up to 65% after 1 year in postmenopausal women.

The VERT-NA study demonstrated significant increases in bone mineral density and vertebral integrity with weekly risedronate use.

Long-term use (3–5 years) is associated with sustained bone protection, especially in combination with calcium and vitamin D

Keep in original packaging, away from heat and moisture

Keep out of reach of children

Buy Actonel Risedronate Tablets Online (Prescription Required)
Available at: EZ Chemist Online Pharmacy (Insert product-specific URL when published)
Actonel, risedronate sodium, bisphosphonate, osteoporosis, bone loss prevention, tablets, Rx, fracture spine hip risk, postmenopausal bone health