Adenosine Injection
Blackmores Conceive Well Gold 28 Tablets + 28 Capsules
Adenosine Injection Australia, SVT treatment, cardiac emergency injection, purinergic agent, adenosine vial use, EZ Chemist antiarrhythmic medication:
What is Adenosine Injection used for?
Adenosine Injection is a rapid-acting intravenous medication used to restore normal heart rhythm in patients with paroxysmal supraventricular tachycardia (PSVT). It works by slowing conduction through the AV node, interrupting re-entry pathways, and restoring sinus rhythm.
Generic Name: Adenosine
Formulation: Injectable solution (IV use only)
Strengths Available: 3 mg/mL in 2 mL or 5 mL vials (commonly 6 mg/2 mL and 12 mg/4 mL)
Route of Administration: Intravenous bolus injection
Availability: Prescription Only (Schedule 4 – Australia)
Adenosine (3 mg/mL)

Other Popular/Common Names:
Adenocard (brand in some regions)

PSVT treatment injection

AV nodal blocker

Antiarrhythmic emergency agent

Rapid IV cardiac drug

Mode of Action (How It Works):
Adenosine is a purinergic receptor agonist that acts on A1 adenosine receptors in the atrioventricular (AV) node of the heart. It causes:

Transient AV node conduction block, interrupting re-entry circuits responsible for supraventricular tachycardia

Slowing of the sinus rate, allowing restoration of normal rhythm

Very short half-life (<10 seconds), making it ideal for rapid onset and brief action

It is highly effective in terminating paroxysmal supraventricular arrhythmias that involve the AV node.

Indications / Clinical Uses:
Rapid conversion to sinus rhythm from paroxysmal supraventricular tachycardia (PSVT)

Diagnosis of wide complex tachycardias to distinguish from ventricular tachycardia

Temporarily slows AV node conduction during atrial flutter or atrial fibrillation (diagnostic use)
Initial dose: 6 mg rapid IV bolus

If ineffective within 1–2 minutes: 12 mg IV bolus may be given
Maximum single dose: 12 mg
Administer via central or large peripheral vein, followed immediately by saline flush
Must be administered under continuous ECG monitoring by trained professionals in a hospital or emergency setting.
Prescription Required: Yes

Pregnancy Category: B2 (use only if clearly needed)

Not suitable for home use or over-the-counter

Contraindicated during pregnancy attempts or conception support therapy like Blackmores Conceive Well Gold
Side Effects (Short Duration):
Flushing
Chest pressure or pain

Dyspnoea (shortness of breath)

Light-headedness

Throat tightness

Nausea
Transient arrhythmias (PVCs, bradycardia, AV block) — expected and self-resolving
Bronchospasm (especially in asthmatics)
Seizures

Hypotension

Prolonged asystole (rare in healthy hearts)

Warnings & Precautions:
Use with extreme caution in asthma or COPD patients

Avoid in second- or third-degree AV block, sick sinus syndrome (unless paced)

Not for use in patients with long QT syndrome, ventricular fibrillation, or heart transplant patients (increased sensitivity)

Ensure resuscitation equipment and personnel are available

Avoid combining with Blackmores Conceive Well Gold due to cardiac and hormonal interaction potential
Dipyridamole: Potentiates adenosine; avoid or reduce dose

Methylxanthines (caffeine, theophylline): Block adenosine receptors — may require higher doses

Carbamazepine: May enhance AV block risk

Digitalis: Caution due to additive AV conduction effects

Therapeutic Class: Antiarrhythmic agent

Pharmacologic Class: Purinergic receptor agonist

Regulatory Category: Schedule 4 – Prescription Only Medicine (Australia)

ATC Code: C01EB10

Frequently Asked Questions (FAQs):
Q1. How fast does adenosine work for SVT?
A: Adenosine acts within seconds and usually restores sinus rhythm in less than 30 seconds due to its extremely short half-life.

Q2. Can adenosine be used with Blackmores Conceive Well Gold?
A: No. Adenosine is used in emergencies and is not recommended for individuals trying to conceive or pregnant due to limited safety data.

Q3. What if adenosine does not work?
A: If the 6 mg and 12 mg doses fail, other antiarrhythmics like verapamil or beta-blockers may be used. Always under specialist care.

Q4. Is adenosine safe in pregnancy?
A: Classified as Pregnancy Category B2 in Australia. Should only be used when clearly needed in life-threatening arrhythmias.

Q5. Does adenosine stop the heart?
A: It may cause transient asystole or AV block for a few seconds, but this is part of its therapeutic effect and usually resolves spontaneously.

Clinical Studies & Efficacy:
Adenosine has a success rate of >90% in terminating AV nodal reentrant tachycardia (AVNRT), making it the first-line agent in emergency departments worldwide.

Supported by ACLS (Advanced Cardiac Life Support) guidelines and major cardiology societies

Short action makes it safe for diagnostic use to distinguish wide complex tachycardias
Store at 2°C to 8°C (refrigerated)
Do not freeze
Protect from light

Use immediately once opened or drawn into a syringe
Buy Adenosine Injection Online (For Hospital Supply Only)
Available at: EZ Chemist Online Pharmacy (Insert product-specific link if applicable for hospital/pharmacy supply)
Adenosine Injection, purinergic agent, SVT treatment, AV nodal blocker, injection, Rx, arrhythmia emergency, ECG monitored, EZ Chemist cardiac rhythm control