Alfanil Syrup (Paracetamol) – Analgesic & Antipyretic for Pain and Fever | EZ Chemist Online Pharmacy
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Alfanil Paracetamol Syrup – Safe Pain Relief & Fever Reduction for Children and Adults | Buy Online at EZ Chemist
What is Alfanil Syrup used for?
Alfanil Syrup contains paracetamol (acetaminophen), a non-opioid analgesic and antipyretic used to relieve mild-to-moderate pain and reduce fever. It works by inhibiting prostaglandin synthesis in the brain and blocking pain pathways.
Brand Name: Alfanil Syrup

Generic Name: Paracetamol (also known as Acetaminophen)
Form: Oral Syrup / Suspension

Typical Strength: 120 mg/5 mL (children’s formulation) or 250 mg/5 mL (junior/adult formulation)
Drug Class: Analgesic and Antipyretic
Availability: Over-the-counter in India; prescription not required
Manufacturers: Commonly available as Alfanil, Calpol, Panadol, Tylenol equivalents
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Paracetamol (Acetaminophen)
Mechanism: Inhibits prostaglandin G/H synthase (COX-2) in the central nervous system, modulating pain and temperature regulation
Onset: Approximately 30 minutes; duration 4–6 hours
International Generics: Tylenol, Panadol, Calpol, Alvedon

Related Products: Combined OTC formulations for cold and flu relief
Paracetamol provides analgesia and antipyresis through inhibition of central prostaglandin synthesis and modulation of serotonergic and endocannabinoid pain pathways. It exhibits minimal peripheral anti-inflammatory activity
Reduce fever from infections or immunizations
Relieve pain including headache, toothache, menstrual cramps, musculoskeletal pain, earache, and sore throat
Manage post-vaccination fever in infants and children
Age Group Strength Dose per Occasion Frequency Max Daily Dose
Infants (2–3 mo) 120 mg/5 mL 2.5 mL (60 mg) Every 4 hrs, max 4 doses 240 mg/day
Children (6 mo–6 yr) 120 mg/5 mL 5–10 mL (120–240 mg) Every 4 hrs, max 4 doses 1 g/day (15 mg/kg × 4)
Children (>6 yr) 250 mg/5 mL 5–10 mL (250–500 mg) Every 4–6 hrs, max 4 doses 4 g/day
Adults 250 mg/5 mL or tablet 500–1000 mg Every 4–6 hrs, max 4 g/day 4 g/da
Shake well before use
Use dosing spoon or syringe provided
May be taken with or without food
Route: Oral
Onset: 30 minutes post-administration
Metabolism: Liver (via CYP pathway)
Half-life: ~2 hours
Excretion: Metabolites eliminated via urine
Rare: nausea, rash, headache

Generally well tolerated when used at recommended doses
Wikipedia
Liver toxicity with overdose or chronic high-dose use

Rare allergic reactions (hypersensitivity, skin rashes)

Blood disorders like agranulocytosis (very rare)
Do not exceed 4 g/day in adults

Avoid concurrent alcohol consumption or hepatic disease

Monitor use in patients with existing liver or kidney disease

For prolonged use (>10 days adults, >5 days children), consult a physician

In overdose, seek emergency care—even if asymptomatic—due to latent liver damage
Wikipedia
TN Meds
Warfarin & oral anticoagulants: Possible INR increase with high doses
Lippincott Journals
Enzyme inducers (e.g. carbamazepine, phenobarbital): ↑ risk of hepatotoxic metabolite accumulation

Proton pump inhibitors/antacids: Alter absorption but not clinical effect

Clinical Insight: A geriatric study reported ~10% of hospitalized elderly had potential adverse interactions, chiefly with warfarin and phenytoin
Store at room temperature (below 25°C)

Protect from light and moisture

Keep bottle tightly sealed
Keep out of reach of children
Frequently Asked Questions (FAQs):
Q1: What is Alfanil Syrup used for?
It is a liquid form of paracetamol used to reduce fever and relieve mild to moderate pain in all age groups.

Q2: Is it safe for infants?
Yes, suitable from 2 months onward. Dose carefully as per weight; consult a pediatrician for very young infants.

Q3: Can I give this after vaccinations?
Yes, it is commonly used to manage post-immunization fever in infants.

Q4: Can adults take it?
Yes—5 mL provides 250 mg; adult dose is typically 500–1000 mg every 4–6 hours, not exceeding 4 g/day.

Q5: Can I take with other medicines?
Generally safe, but if you are on blood thinners (warfarin) or enzyme-inducing drugs, inform your doctor.

Q6: What if I miss a dose?
Take as soon as remembered unless next dose is due. Do not double dose.

Clinical References:
Paracetamol drug monograph (Drugs.com, 2025)

Paracetamol dosage guidelines (NHS, UK)
Review of paracetamol drug interactions (PubMed, 2005)

Geriatric interaction study (Journal of Pharmaceutics, 2020)
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