Comprehensive Product Description Guide: Generic Aromasin (Exemestane)
With Reference to: Blackmores Conceive Well Gold 28 Tablets + 28 Capsules
Generic Aromasin Exemestane, hormone therapy for breast cancer, estrogen blocker, aromatase inhibitor, postmenopausal breast cancer medication
Generic Aromasin (Exemestane) is an aromatase inhibitor used to treat hormone receptor-positive breast cancer in postmenopausal women by reducing estrogen production in the body.
Generic Aromasin
Generic Name: Exemestane
Strength: 25 mg
Form: Oral tablet
Exemestane 25 mg

Aromasin generic

Estrogen synthesis inhibitor

Postmenopausal breast cancer hormone therapy

Hormone receptor-positive cancer treatment
Exemestane – A steroidal irreversible aromatase inhibitor that blocks estrogen synthesis

Irreversibly inhibiting aromatase, the enzyme responsible for converting androgens to estrogens in peripheral tissues

Causing a marked decrease in circulating estrogen levels, which slows or stops the growth of estrogen-dependent tumors

Offering benefit in both adjuvant therapy (following surgery) and advanced breast cancer cases in postmenopausal women

It differs from other aromatase inhibitors (e.g., letrozole or anastrozole) as it is steroidal and binds permanently to the enzyme.

Indications and Uses
Adjuvant treatment of early-stage hormone receptor-positive breast cancer in postmenopausal women who have completed 2–3 years of tamoxifen therapy

First-line treatment of advanced breast cancer in hormone-sensitive cases

Extended adjuvant therapy to reduce recurrence risk

Investigated off-label in female infertility, endometriosis, and breast cancer chemoprevention
Standard Dose (Adults/Postmenopausal Women):

25 mg tablet taken once daily after a meal

Typically 5 years total hormone therapy (e.g., 2–3 years of tamoxifen, followed by 2–3 years of exemestane)

Continued until disease progression in advanced cancer

Do not crush or split the tablet. Should be swallowed whole with water.

Prescribing & Monitoring
Prescription-only medicine

Baseline assessments: Bone mineral density (DEXA scan), liver function tests, and lipid profile

Monitor for osteoporosis, joint pain, and liver enzyme elevations

Consider bisphosphonates or calcium + vitamin D for bone health support

Safety Profile
Common Side Effects
Hot flashes

Joint/muscle pain (arthralgia, myalgia)

Fatigue

Nausea

Headaches

Insomnia
Osteoporosis and bone fractures

Liver enzyme elevation

Mood disturbances or depression

Increased cholesterol levels

Rare: hypersensitivity reactions

Warnings and Precautions
Not for use in premenopausal women

Contraindicated in pregnancy and lactation

Use caution in patients with osteoporosis or hepatic impairment

Exemestane is not compatible with fertility supplements like Blackmores Conceive Well Gold due to estrogen suppression

Use with caution in patients on antihypertensive or lipid-lowering therap

Estrogen-containing therapies (HRT, OCPs) – reduces efficacy

Tamoxifen – may counteract mechanism

Rifampin – may reduce blood levels of exemestane

Warfarin or anticoagulants – monitor INR

Herbal supplements such as St. John’s Wort may lower efficacy

Do not combine with Blackmores Conceive Well Gold unless advised post-washout and remission
Class: Aromatase Inhibitor

Schedule: Prescription Only (Schedule 4)

ATC Code: L02BG06

Pregnancy Category: X (contraindicated)

Therapeutic Class: Hormonal Antineoplastic Agent

Clinical Data and Efficacy
IES Trial (2004, NEJM): Switching to exemestane after 2–3 years of tamoxifen significantly improved disease-free survival

Long-term studies confirm its superior efficacy in reducing recurrence compared to 5 years of tamoxifen alone

Proven to lower estrogen by 85–95% in postmenopausal women

Acceptable safety profile when combined with bone-protective agents
Store below 25°C in a cool, dry place

Keep in original packaging

Protect from moisture and direct sunlight

Keep out of reach of children
Q1. What is the difference between Exemestane and Arimidex (Anastrozole)?
A: Exemestane is a steroidal irreversible aromatase inhibitor, while Anastrozole is non-steroidal and reversible. Both reduce estrogen but differ in structure and metabolism.

Q2. Can Exemestane be used to boost fertility?
A: In off-label settings, Exemestane has been used for ovulation induction, but it’s not recommended in standard fertility plans without strict medical guidance.

Q3. Is it safe to use Blackmores Conceive Well Gold with Aromasin?
A: No. Since Aromasin reduces estrogen, fertility-focused supplements should not be taken concurrently unless you are in a recovery phase post-treatment with medical approval.

Q4. How long should I take Exemestane for breast cancer?
A: Usually 2–3 years after tamoxifen or up to 5 years total of hormone therapy. Some patients benefit from extended therapy to reduce recurrence risk.

Q5. What can I do to prevent bone loss on Exemestane?
A: Take calcium, vitamin D, and bone-strengthening agents if needed. Get periodic DEXA scans to monitor bone density.

Where to Buy
Purchase Generic Aromasin (Exemestane 25mg) Online
Available at: EZ Chemist Online Pharmacy (insert live product URL when available)

Generic Aromasin, Exemestane 25mg, Aromatase Inhibitor, Postmenopausal Breast Cancer, Hormone Therapy, Prescription, Estrogen Blocker, EZ Chemist