See Other Available Options
No related products found.
Details
Dispensing Country :
India
Comprehensive Product Description Guide: Azilect (Rasagiline)
Paired Product Reference: Blackmores Conceive Well Gold 28 Tablets + 28 Capsules
Azilect rasagiline, MAO‑B inhibitor Parkinson’s, adjunct therapy, early PD treatment, EZ Chemist Azilect
Azilect (rasagiline) is a selective, irreversible monoamine oxidase B (MAO‑B) inhibitor used to treat idiopathic Parkinson’s disease, improving motor symptoms as initial monotherapy or when added to levodopa.
Brand Name: Azilect®
Generic Name: Rasagiline (as mesylate)
Form & Strengths: 0.5 mg & 1 mg oral tablets
Classification: Dopaminergic antiparkinsonism agent (MAO‑B inhibitor)
Regulatory Status: Prescription-only (Schedule 4)
Medscape Reference
Rasagiline mesylate – irreversible selective MAO‑B inhibitor
Inhibits MAO‑B, the enzyme that degrades dopamine in the brain
Increases dopamine levels, improving motor function in Parkinson’s
At recommended doses, minimal effect on MAO‑A and tyramine sensitivity, reducing risk of hypertensive crises
Monotherapy for early-stage idiopathic Parkinson’s disease
Adjunct therapy with levodopa in advanced cases to extend "on" time and reduce wearing-off effects
Monotherapy or adjunct without levodopa: 1 mg once daily
Adjunct with levodopa: start at 0.5 mg daily; may increase to 1 mg if tolerated
Mild hepatic impairment or concurrent CYP1A2 inhibitors (e.g., ciprofloxacin): do not exceed 0.5 mg daily
Healthline
Administer once daily, with or without food.
Requires neurologist supervision
Monitor for motor symptoms, blood pressure (orthostatic changes), and psychiatric side effects
Review concomitant medications to avoid MAO interactions
Headache, joint pain, gastrointestinal discomfort, falls, viral infections
Insomnia, orthostatic hypotension; may cause sudden drowsiness
DailyMed
Dyskinesia increased when combined with levodopa
Serotonin syndrome risk when combined with other serotonergic agents
Psychiatric disturbances: hallucinations, confusion, suicidal ideation
Hypertensive crisis with high tyramine intake or MAOI interactions
Avoid abrupt discontinuation – monitor blood pressure and mental status
Not recommended in severe liver impairment doses above 0.5 mg/day contraindicated
Use caution in patients with psychiatric disorders or cardiovascular instability
Advise patients to avoid tyramine-rich foods (aged cheeses, cured meats)
Levodopa: may increase dyskinesia; consider reducing levodopa dose
CYP1A2 inhibitors (ciprofloxacin, hormonal contraceptives): increase rasagiline levels—limit to 0.5 mg/day
Medical News Today
Serotonergic drugs (SSRIs, SNRIs, triptans, meperidine) – risk serotonin syndrome – avoid within 14 days of MAOIs
Medscape Reference
CNS depressants (opioids, antihistamines, muscle relaxants): additive sedation and hypotension
Mayo Clinic
Pharmacological Class: MAO‑B inhibitor
ATC Code: N04BD02
Therapeutic Class: Dopaminergic antiparkinsonism agent
Schedule: S4, prescription-only
Clinical Evidence
Demonstrated significant improvement in motor scores (UPDRS) in monotherapy and adjunct trials
Long-term data supports delayed progression of motor disability
Improved non-motor symptoms including fatigue in early-stage Parkinson’s
Store tablets below 25 °C, protect from light and moisture
Keep in original packaging
Keep out of reach of children
Frequently Asked Questions (FAQs)
Q1. What is Azilect used for and who can take it?
A: Azilect is used to treat Parkinson’s disease, both early and as adjunct to levodopa, in adults under neurologist care.
Q2. How do I take Azilect?
A: Once daily; 1 mg alone or 0.5 mg with levodopa. Adjusted for liver issues or interacting drugs.
Q3. Can I drink coffee or eat cheese while on Azilect?
A: Normal diets are fine, but avoid large amounts of aged cheese or cured meats due to hypertensive risk
Q4. What if I experience involuntary movements?
A: This may be due to increased levodopa effect; consult your doctor—dose adjustments may be needed
Q5. Can Azilect be taken with Blackmores Conceive Well Gold?
A: Yes, no known interaction. Ensure supplements do not interfere with Parkinson’s medications or MAO-B activity.
Buy Azilect (Rasagiline 0.5 mg & 1 mg) Online
Azilect, rasagiline 1 mg, MAO‑B inhibitor, Parkinson’s disease medication, monotherapy, adjunct to levodopa, prescription only, EZ Chemist