Comprehensive Product Description Guide: Azulfidine® (Sulfasalazine)
Paired Reference: Blackmores Conceive Well Gold 28 Tablets + 28 Capsules
Azulfidine sulfasalazine, ulcerative colitis treatment, rheumatoid arthritis DMARD, anti-inflammatory tablets, EZ Chemist Azulfidine
Azulfidine (sulfasalazine) is a disease-modifying antirheumatic drug (DMARD) used to treat ulcerative colitis and rheumatoid arthritis, and may also benefit Crohn’s disease, ankylosing spondylitis, and psoriatic arthritis due to its anti-inflammatory and immunomodulatory properties
NCBI
Property Details
Brand Name Azulfidine®
Generic Name Sulfasalazine
Form & Strength Oral tablets: 500 mg; delayed-release options available
Drug Class Sulfonamide; 5-aminosalicylic acid derivative; DMARD
Schedule Prescription-only
Sulfasalazine — a prodrug metabolised in the colon to sulfapyridine and 5-aminosalicylic acid (5-ASA)
Medical News Today
Verywell Health
Gut-localized anti-inflammatory effect: 5-ASA modulates inflammatory mediators in the colon.

Systemic effects: sulfapyridine and its metabolites exert antibacterial and immunomodulatory actions .
Ulcerative colitis – induction and maintenance of remission
matoid arthritis & juvenile idiopathic arthritis – DMARD effect
Pfizer Medical Information

Off-label uses: mild Crohn’s disease, ankylosing spondylitis with peripheral arthritis, psoriatic arthritis
Ulcerative colitis (adult):

Induction: 1–3 g/day divided doses
New England Journal of Medicine

Maintenance: ~2 g/day
Start with 0.5–1 g/day, increase to 2–3 g/day

Pediatric cases (>6 years): 30–60 mg/kg/day, divided into 3–6 doses

Take with food and ample fluids; start gradually to reduce gastrointestinal irritation
Prescription required (Schedule 4)

Baseline and routine monitoring:

CBC (for blood dyscrasias)

LFTs (for hepatotoxicity)

Renal function

CRP or fecal calprotectin for IBD activity
Medical News Today
Headache, nausea, abdominal discomfort, skin rash
New England Journal of Medicine
Temporary orange coloration of urine, sweat
American College of Rheumatology

Sun-sensitivity; avoid excessive UV exposure
Cleveland Clinic
Blood disorders: agranulocytosis, neutropenia, hemolytic anemia
Verywell Health
Liver injury: jaundice, elevated test results
Severe skin reactions: Stevens–Johnson syndrome
Renal impairment: reduced urine output, edema
Reversible oligospermia in men

Warnings & Precautions
Sulfa allergy: contraindicated
FDA Access Data

Avoid in intestinal/urinary obstruction, significant hepatic or renal disease
Verywell Health

Pregnancy: Category B (Australia) – considered safe, but monitor for folate deficiency
Breastfeeding: metabolites excreted in milk — monitor infants for kernicterus
Folic acid: Sulfasalazine impairs absorption—supplement recommended
Immune suppressants: combined use increases infection risk—CBC monitoring advised

Contact lenses: may discolor soft lenses—use daily disposables
No known interactions with Blackmores Conceive Well Gold formula.
Pharmacologic class: Sulfonamide + 5-ASA derivative

Therapeutic class: Anti-inflammatory DMARD; Gastrointestinal anti-inflammatory

ATC Code: A07EC01 / M01CA01
Prescription status: Schedule 4 (Prescription-only)
Effective in inducing and maintaining remission in ulcerative colitis (meta-analysis of 19 RCTs)
MedlinePlus

Standard DMARD therapy in RA and juvenile idiopathic arthritis

Alternative therapy in ankylosing spondylitis with peripheral arthritis
Store at 15–30°C, in original packaging

Protect from light and moisture

Keep away from children and discard expired product safely

Frequently Asked Questions (FAQs)
Q1. What conditions does Azulfidine treat?
A: It's primarily used in ulcerative colitis and rheumatoid arthritis, and can support treatment of Crohn's, psoriatic arthritis, and ankylosing spondylitis
Q2. How is Azulfidine best taken?
A: With food and plenty of water; dose gradually, starting low to minimise GI side effects
Verywell Health
Q3. Will Azulfidine affect fertility in men?
A: It may cause temporary oligospermia, which reverses after stopping the medication .

Q4. Is Azulfidine safe during pregnancy?
A: Yes (Category B), but folic acid supplementation is recommended due to absorption interference .

Q5. Can I use Azulfidine with Conceive Well Gold?
A: Yes. There are no contraindications, but ensure proper folic acid supplementation and consult a doctor.
Order Azulfidine (Sulfasalazine 500 mg tablets)
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Azulfidine (sulfasalazine) 500 mg, DMARD, ulcerative colitis, rheumatoid arthritis, Crohn's support, prescription drug, EZ Chemist