Generic Bricanyl® (Terbutaline Sulfate)
Compared with: Blackmores Conceive Well Gold 28 Tablets + 28 Capsules

Generic Bricanyl (Terbutaline Sulfate) is a short‑acting β₂‑adrenergic agonist available as inhaler, nebulizer solution, oral tablets, and syrup. It provides rapid relief of acute bronchospasm in asthma and COPD by relaxing airway smooth muscle, with onset in 15 minutes and duration up to 6 hours
Terbutaline Sulfate – 0.5 mg per inhalation (Turbuhaler), 250 µg/mL nebulizer solution, 2.5 mg tablets, 1 mg/mL syrup.
Terbutaline (generic)

Bricanyl® Turbuhaler® (DPI)

Brethine® (US inhaler)

Marex®, Bronclyn® (other brands)
Terbutaline is a selective β₂‑adrenergic receptor agonist. By binding to β₂ receptors on bronchial smooth muscle, it activates adenylate cyclase, increases cyclic AMP, and induces smooth‑muscle relaxation. This leads to bronchodilation, decreased airway resistance, and relief of wheezing and dyspnea
Acute Bronchospasm Relief in asthma, chronic bronchitis, and emphysema (patients ≥12 years)
Maintenance Therapy for reversible airway obstruction (inhaler or nebulizer)

Off‑Label (Hospital Only): Tocolysis in threatened preterm labor (IV or SC) for up to 48 hours under strict monitoring
U.S. Food and Drug Administration
Formulation Age Group Dose Frequency
Turbuhaler DPI (0.5 mg) ≥12 years 1–2 inhalations (0.5–1.0 mg) As needed; up to 24 inhalations/24 h
Medsafe
Nebulizer (250 µg/mL) ≥12 years 0.5 mL (125 µg) – 1 mL (250 µg) Every 4–6 h as required
Oral Tablets (2.5 mg) ≥12 years 2.5–5 mg Every 6 h as needed
Syrup (1 mg/mL) ≥2 years 0.1 mg/kg (max 5 mg) Every 6 h as needed
IV Infusion (tocolysis) Hospital only 2.5–5 µg/min initial; titrate Continuous for ≤48 h (max)

Administration Tips: Inhaler — shake (if pMDI), exhale fully, inhale deeply during actuation, hold breath 5–10 s. DPI — load and inhale forcefully.
Medsafe

Missed Dose: Administer when remembered unless close to next dose; do not double.

Formulations: Metered‑dose inhaler, dry‑powder inhaler (Turbuhaler), nebulizer solution, oral tablets, syrup, injectable

Legal Status: OTC for inhaler/tablet/syrup in asthma; prescription for injectable and off‑label uses

Pregnancy: Category C – avoid routine use; IV tocolysis only in hospital emergencies, ≤48 h
U.S. Food and Drug Administration

Breastfeeding: Low milk levels; benefits outweigh minimal risk

Pediatric: Inhalation ≥3 years under guidance; oral and injectable only under specialist supervision

Elderly: No specific adjustment, but monitor for tachycardia and hypotension
Tremor, nervousness, headache

Tachycardia, palpitations

Muscle cramps

Less Common/Serious:

Hypokalemia, hyperglycemia

Paradoxical bronchospasm (rare)

Pulmonary edema (IV use)

Uterine tachysystole (tocolysis)
U.S. Food and Drug Administration
Cardiac Disease: Use cautiously in arrhythmias, ischemic heart disease

Diabetes: Monitor blood glucose—may induce hyperglycemia

Electrolytes: Check potassium in long‑term or high‑dose use

Preterm Labor (Off‑Label): Do not use oral terbutaline for prolonged tocolysis; risk of serious maternal events
U.S. Food and Drug Administration
Therapeutic Class: Bronchodilator

Pharmacologic Class: Short‑Acting β₂‑Agonist (SABA)

Legal Category: OTC for inhalers/tablets; Rx for off‑label and injectable
Non‑Selective β‑Blockers: Antagonise effect—avoid concurrent use

Diuretics / Corticosteroids: Potentiated hypokalemia—monitor serum K⁺

MAO Inhibitors / TCAs: Enhanced cardiovascular effects—monitor closely

Digoxin: May enhance arrhythmogenic risk
A randomized study showed Turbuhaler 0.5 mg provided lung-function improvement comparable to MDI with spacer

Meta‑analyses confirm terbutaline inhalation onset in 15 minutes, peak at 60 minutes, duration up to 6 hours
Mayo Clinic
FAQs – Generic Bricanyl (Terbutaline)
Q1. How quickly will I feel relief?
A: Within 15 minutes of inhalation; effect lasts up to 6 hours
Mayo Clinic
Q2. Can I use it before exercise?
A: Yes—take 15 minutes prior to activity to prevent exercise‑induced bronchospasm.
Q3. What if I exceed 24 inhalations in 24 h?
A: Seek medical attention; risk of tachycardia and tremor increases.

Q4. Can children use the Turbuhaler?
A: Suitable for children ≥3 years who can master inhalation technique; supervise use.

Q5. Is oral terbutaline as effective as inhaled?
A: Inhaled delivery is preferred for rapid bronchodilation; oral used when inhalation is not possible.

Q6. Can I taper off Bricanyl?
A: No taper needed for inhaled/short‑term oral; discontinue as symptoms resolve.

Q7. How should I store my inhaler?
A: Room temperature (15–25 °C), dry place; protect from moisture and heat.
Bricanyl Turbuhaler, Terbutaline Inhaler, Short‑Acting Beta‑Agonist, Asthma Reliever, Bronchodilator DPI, COPD Rescue Inhaler, EZ Chemist, Terbutaline Syrup, Acute Bronchospasm Treatment, Off‑Label Tocolytic