Buspar (Buspirone Hydrochloride) – Non-Sedating Anxiolytic | EZ Chemist Online Pharmacy
Buy Buspar (Buspirone) Online – Non-Benzodiazepine Anxiety Treatment with Minimal Sedation | EZ Chemist

What is Buspar used for?
Buspar (Buspirone Hydrochloride) is a prescription anti-anxiety medication used for the management of Generalized Anxiety Disorder (GAD). Unlike benzodiazepines, it does not cause sedation or dependency and is ideal for long-term anxiety control.
Generic Name: Buspirone Hydrochloride

Brand Name: Buspar

Other Names: Anxiron, Ansial, Bespar

Drug Class: Azapirone anxiolytic

Form: Oral tablets

Strengths Available: 5 mg, 10 mg, 15 mg, 30 mg

ATC Code: N05BE01

Availability at EZ Chemist: Prescription required

Order Buspar Tablets Online – EZ Chemist
Buspirone Hydrochloride
A non-sedating anxiolytic agent that works by modulating serotonin and dopamine receptors in the brain.
Buspirone

Buspar

Anxiron

Buspican

Azapirone anxiolytic

Non-benzodiazepine anti-anxiety tablet

Buspirone acts as a partial agonist at 5-HT1A receptors and affects dopamine D2 receptors, which modulates neurotransmission associated with anxiety and fear.

No sedation

No muscle relaxant or anticonvulsant activity

No risk of withdrawal or dependence
Generalized Anxiety Disorder (GAD)

Chronic anxiety symptoms without depression

Adjunctive therapy in depression-related anxiety (off-label)

Standard Adult Dosage:

Initial dose: 7.5 mg twice daily

Titration: Increase by 5 mg every 2–3 days as needed

Maintenance dose: 15–30 mg/day in divided doses

Maximum dose: 60 mg/day

Take with or without food, but maintain consistency. Avoid grapefruit juice as it may affect drug levels.

Requires a valid prescription

Takes 1–3 weeks to show full therapeutic effect

Not suitable for as-needed anxiety relief (unlike benzodiazepines)

Should be taken consistently for best results

Not habit-forming

Safe for long-term use under medical supervision

Does not interact with GABA receptors, so no sedation or addiction
Mild Serious (Rare)
Dizziness Serotonin Syndrome (with SSRIs)
Nausea EPS (Extrapyramidal symptoms)
Headache Tachycardia
Nervousness Seizures (very rare)
Avoid alcohol while taking Buspar

Not recommended for use with MAO inhibitors

Caution in renal or hepatic impairment

Monitor in patients with Parkinson’s disease due to dopamine effects

Not for pregnancy (Category B) unless clearly needed

Therapeutic Class: Anxiolytic

Pharmacological Class: Azapirone

Schedule: Prescription-only

Pregnancy Category:
Drug/Class Interaction
MAO inhibitors Hypertensive crisis
SSRIs/SNRIs Risk of serotonin syndrome
CYP3A4 inhibitors Increases Buspar levels
Grapefruit juice Inhibits metabolism – avoid
Diazepam Decreased effectiveness of both drugs

Rickels et al., J Clin Psychopharmacol (1982):
Buspirone was significantly more effective than placebo in treating GAD without sedative effects.

Davidson et al., Arch Gen Psychiatry (1990):
Demonstrated Buspirone’s long-term efficacy over 6 months with minimal adverse events.
Found that Buspirone was a viable option in patients unable to tolerate SSRIs or benzodiazepines.

FAQs – Buspar (Buspirone)
Q1: Is Buspar addictive like benzodiazepines?
No. Buspar is non-addictive and has no known withdrawal symptoms.

Q2: How long does it take for Buspar to work?
It may take 1–3 weeks to notice significant improvement in anxiety.

Q3: Can I take Buspar only when needed?
No. Buspar must be taken regularly to be effective. It is not suitable for PRN (as-needed) use.

Q4: Can Buspar be combined with SSRIs?
It can be, under medical supervision, though there is a risk of serotonin syndrome.

Q5: Is Buspar safe during pregnancy?
Category B – Not teratogenic in animals, but human data is limited. Consult your doctor.
Store at 20°C to 25°C (68°F to 77°F)

Protect from moisture and heat

Keep out of reach of children

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