Comprehensive Product Description Guide: Cipro Syrup (Ciprofloxacin Oral Suspension)
What is Cipro Syrup used for
Cipro Syrup, containing ciprofloxacin, is an oral antibiotic used to treat a wide range of bacterial infections, including respiratory tract infections, urinary tract infections, gastrointestinal infections, and certain types of typhoid. It works by inhibiting bacterial DNA replication, effectively stopping the growth of harmful bacteria in children and adults.

Cipro Syrup (Ciprofloxacin Oral Suspension)

Brand Name: Cipro
Generic Name: Ciprofloxacin
Dosage Form: Oral Suspension
Strengths: Commonly 250 mg/5 ml or 500 mg/5 ml
Drug Class: Fluoroquinolone antibiotic

Ciprofloxacin Hydrochloride
Each 5 ml of Cipro Syrup contains ciprofloxacin hydrochloride equivalent to 250 mg or 500 mg of ciprofloxacin, depending on formulation.

Ciprofloxacin Suspension

Ciprobid

Cipro Oral Solution

Fluoroquinolone Antibiotic Syrup

Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA replication, transcription, and repair. This action results in bacterial cell death, making it effective against both Gram-positive and Gram-negative bacteria.

Cipro Syrup is indicated in children and adults for the treatment of:

Urinary tract infections (UTIs)

Respiratory tract infections (including bronchitis, pneumonia)

Gastrointestinal infections (including traveller’s diarrhoea, typhoid fever)

Skin and soft tissue infections

Bone and joint infections

Anthrax post-exposure prophylaxis

Complicated otitis media (off-label in some regions)

Usual Pediatric Dosage (based on infection and weight):

Urinary tract infections: 10–20 mg/kg twice daily for 7–14 days

Typhoid fever: 15–20 mg/kg/day in divided doses

Maximum dose: Should not exceed 500 mg twice daily in children

Adult Dosage (if prescribed as liquid):

Equivalent to 250–750 mg twice daily depending on severity of infection

Shake the bottle well before use

Do not take with dairy products or calcium-fortified juice

Ensure appropriate spacing from antacids, iron, or multivitamins (2 hours before or 6 hours after)

Prescription-only medicine (Schedule 4 in Australia)

Not recommended for use in children under 1 year unless strictly necessary

Should be used only under medical supervision for appropriate bacterial infections

Ciprofloxacin can cause tendon inflammation and rupture, particularly in elderly patients and those on corticosteroids

May affect joint cartilage in growing children—prescribe only when benefits outweigh risks

Monitor for hypersensitivity reactions, especially on first dose

Use with caution in patients with CNS disorders, may cause seizures
Nausea

Diarrhoea

Abdominal pain

Rash

Headache

Serious (less common):

Tendon rupture

QT prolongation

Seizures

Hypersensitivity or anaphylaxis

Photosensitivity

Tendonitis and tendon rupture: Especially in older adults and athletes

Photosensitivity: Avoid excessive sunlight or UV exposure

Neurological effects: Can cause dizziness, confusion, or hallucinations

Avoid in pregnancy and breastfeeding unless essential

Use in children is restricted to certain infections (e.g., complicated UTIs, anthrax)

Ciprofloxacin may interact with:

Antacids containing magnesium, aluminium – reduces absorption

Calcium or iron supplements – space doses to avoid interaction

Tizanidine – contraindicated due to severe hypotension risk

Theophylline – may increase theophylline plasma levels

Warfarin – may enhance anticoagulant effect

CYP1A2 substrates – may alter metabolism of caffeine, clozapine, etc.

FDA and EMA Approved: For select pediatric indications including complicated UTIs and post-anthrax exposure

Randomised trials have demonstrated ciprofloxacin efficacy in treating multidrug-resistant Salmonella typhi

Lancet (2019): Ciprofloxacin shown to reduce symptom duration in travellers’ diarrhoea by up to 2 days

Frequently Asked Questions (FAQs):
Q: What is Cipro Syrup used for in children?
A: Cipro Syrup is primarily used to treat serious bacterial infections such as UTIs, typhoid, and anthrax post-exposure in children when safer alternatives are not effective.

Q: Can Cipro Syrup treat viral infections like cold or flu?
A: No. Cipro is an antibiotic and is not effective against viral infections.

Q: Is Cipro Syrup safe for toddlers?
A: It should only be used under strict medical guidance in children under 5 years and only for specific infections.

Q: Can Cipro Syrup be taken with milk?
A: No. Dairy products can interfere with the absorption of ciprofloxacin. Avoid taking Cipro Syrup with milk or calcium-fortified beverages.

Q: How long does it take for Cipro Syrup to work?
A: Clinical improvement is often seen within 1–3 days of starting therapy, but it is crucial to complete the full course as prescribed.

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