Codral PE Day & Night – 48 Tablets
Effective Day & Night Relief for Cold & Flu Symptoms

Codral PE Day & Night is a dual-pack combination remedy with 24 daytime non-drowsy Tablets and 24 night-time Tablets. It offers multi-symptom relief for cold and flu sufferers aged 12 and over. The Day variant relaxes nasal congestion and reduces pain and fever, while the Night variant adds an antihistamine to promote restful sleep.
Day Tablet (Red):

Paracetamol (Acetaminophen) 500 mg – antipyretic and analgesic

Phenylephrine HCl 5 mg – non-drowsy nasal decongestant

Night Tablet (Orange/Blue):

Paracetamol 500 mg

Phenylephrine HCl 5 mg

Chlorpheniramine Maleate 2 mg – sedating antihistamine

Also commonly referred to as Codral Cold & Flu Day/Night or Codral PE Tablets.

Paracetamol alleviates headache, body aches, and fever by acting on central prostaglandin synthesis.

Phenylephrine stimulates α₁-receptors to reduce nasal mucosal swelling.

Chlorpheniramine blocks H₁-histamine receptors, helping relieve runny nose and promoting drowsiness.

Indications & Uses
Relieves the following symptoms associated with colds or flu:

Headache, fever, body aches, sore throat

Nasal congestion and rhinorrhea

Night Tablets also help with sneezing and itchiness and support sleep

Recommended for adults and adolescents (12+ years)

Tablet Dose Frequency Max / 24 Hours
Day (Red) 2 Tablets (1000 mg paracetamol, 10 mg phenylephrine) Every 4–6 hours as needed Up to 6 Day Tablets (3000 mg paracetamol)
Night (Orange) 2 Tablets (1000 mg paracetamol, 10 mg phen) At bedtime, as needed Up to 2 Night Tablets (2000 mg paracetamol)

Stop after: Adults – 3 days; Children (12–17) – 48 hours

Safety, Side Effects & Warnings
Common: Nausea, dry mouth, dizziness, drowsiness (night Tablets), insomnia, restlessness
Serious: Urinary retention, seizures, breathing difficulty, swelling, rash, arrhythmia, liver damage with overdose
Overdose risk: Acute liver failure from paracetamol; seek urgent medical help

Contraindications:

<12 years; allergy to components; concurrent paracetamol; MAO inhibitor use; narrow-angle glaucoma; severe hypertension or heart disease; alcoholism; prostatic hypertrophy; bladder neck obstruction; symptomatic ulcers

Consult doctor if hypertensive, diabetic, thyroid issues, heart or liver disease

Avoid alcohol and CNS depressants; may impair driving
medicinestomidnight.co.nz

Night Tablets cause sedation; do not combine with other antihistamines

Drug Interactions
Phenylephrine may increase effects of stimulants (e.g., amphetamines, SSRIs) – monitor blood pressure/heart rate

Anticoagulants (warfarin) – monitor INR, especially during prolonged paracetamol usage

MAO inhibitors – contraindicated due to sympathomimetic and anticholinergic risk

Drug Classification
Paracetamol: Analgesic/antipyretic

Phenylephrine: Sympathomimetic decongestant

Chlorpheniramine: First-generation H₁ antihistamine

Status: OTC cold & flu relief (pharmacy-only in some areas)

What is Codral PE Day & Night used for?
Codral PE Day & Night provides effective daytime relief from cold and flu symptoms using paracetamol and phenylephrine, and nighttime relief with added chlorpheniramine to ease sneezing and support sleep.

Feature Codral PE Day & Night Blackmores Conceive Well Gold
Purpose Over-the-counter cold & flu relief Preconception efficacy and nutrition
Active Ingredients Paracetamol, Phenylephrine, Chlorpheniramine Folate, DHA, Iodine, CoQ10, Iron, B-vitamins
Application Oral film-coated Tablets Tablets & softgel combination
User Audience Adults & teens (12+ years) Women planning pregnancy

❓ Frequently Asked Questions (FAQs)
Can I take Codral with heart disease or high blood pressure?
Consult your doctor—phenylephrine may raise blood pressure; monitor closely.

Is it safe during pregnancy?
Paracetamol is allowed; phenylephrine and chlorpheniramine should be used only if advised by a healthcare provider.

Can I drink alcohol?
No—combined sedation, liver strain, and increased side effects.

What if I miss a dose?
Take as soon as possible, but do not exceed maximum dose in 24 hours.

Can I take it longer than 3 days?
Do not exceed recommended duration without a healthcare provider’s advice.

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