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Dispensing Country :
India
Comprehensive Product Description Guide: Amaryl (Glimepiride)
Paired Product Reference: Blackmores Conceive Well Gold 28 Tablets + 28 Capsules
Retailer: EZ Chemist Online Pharmacy
Amaryl glimepiride diabetes tablets, type 2 diabetes medicine Australia, sulfonylurea glucose control, EZ Chemist glimepiride
Amaryl is an oral sulfonylurea antidiabetic medication that contains glimepiride. It is used to manage type 2 diabetes mellitus by increasing insulin secretion from the pancreas and improving glucose utilisation in the body.
Amaryl Tablets
Generic Name: Glimepiride
Form: Oral tablet
Strengths Available: 1 mg, 2 mg, 3 mg, 4 mg
Drug Class: Sulfonylurea antidiabetic agent
Availability: Prescription Only (Schedule 4)
Glimepiride – a third-generation sulfonylurea used in type 2 diabetes
Glimepiride
Amaryl (brand name by Sanofi)
Oral hypoglycemic agent
Sulfonylurea antidiabetic
Type 2 diabetes blood sugar control tablet
Amaryl (glimepiride) lowers blood glucose by:
Stimulating pancreatic β-cells to release insulin
Enhancing peripheral tissue sensitivity to insulin
Improving glucose uptake and metabolism
It works best when pancreatic function is preserved, and is often used as first-line or adjunct therapy in type 2 diabetes.
Management of Type 2 Diabetes Mellitus
Use in combination with metformin, insulin, or other oral antidiabetics
Helps reduce long-term diabetic complications by improving glycemic control
1 mg to 2 mg once daily, taken with breakfast or first main meal
Titrated based on response at 1–2 week intervals, up to max 8 mg/day
Tablets should be swallowed whole with a glass of water. Avoid skipping meals after administration.
Prescription required (Schedule 4)
Suitable for adults with type 2 diabetes, especially when diet and exercise alone are insufficient
Not indicated for type 1 diabetes or diabetic ketoacidosis
Use cautiously in elderly or renal/hepatic impairment (start at lower dose)
Hypoglycemia (low blood sugar)
Dizziness Headache Nausea
Weight gain
Liver enzyme abnormalities
Allergic skin reactions
Hematological changes (e.g. thrombocytopenia, leukopenia)
Visual disturbances (transient)
Risk of hypoglycemia especially with irregular meals or excessive alcohol
Avoid in type 1 diabetics or during diabetic ketoacidosis
Dose adjustments needed in renal or hepatic dysfunction
May mask symptoms of hypoglycemia when combined with beta-blockers
Not recommended in pregnancy; switch to insulin
Avoid use while breastfeeding – excreted in small amounts in milk
Increased hypoglycemia risk with:
NSAIDs
Beta-blockers
ACE inhibitors
Alcohol
Clarithromycin
Thiazide diuretics
Corticosteroids
Phenytoin
Oral contraceptives
Minimal direct interaction, but monitor for gastrointestinal absorption delays if taken together
Conceive Well Gold contains iodine, iron, folic acid, which do not impact glimepiride action but spacing doses is advised
Pharmacologic Class: Sulfonylurea
Therapeutic Class: Oral antidiabetic agent
Regulatory Class (Australia): Schedule 4 (Prescription Only)
ATC Code: A10BB12
Frequently Asked Questions (FAQs):
Q1. What is Amaryl used for?
A: Amaryl is used to manage type 2 diabetes in adults by lowering blood glucose when diet and lifestyle measures alone are not sufficient.
Q2. Can Amaryl be taken with Blackmores Conceive Well Gold?
A: Yes, but spacing out administration by 1–2 hours is advised. Consult a physician if planning pregnancy.
Q3. Is Amaryl safe during pregnancy?
A: No. Insulin is preferred during pregnancy to avoid risk to the fetus. Always consult your doctor.
Q4. Can Amaryl cause hypoglycemia?
A: Yes, especially if meals are skipped, after strenuous activity, or with alcohol. Monitor blood sugar regularly.
Q5. How long does Amaryl take to work?
A: It begins to work within 2–3 hours of ingestion, with effects lasting up to 24 hours.
Clinical Evidence:
Glimepiride is widely studied and has non-inferior efficacy to glibenclamide with lower risk of hypoglycemia
Proven to reduce HbA1c levels by ~1–2% over 12–16 weeks
Often combined with metformin or DPP-4 inhibitors in clinical protocols
Store below 30°C
Keep in original packaging
Protect from moisture and heat
Keep out of reach of children
Buy Amaryl (Glimepiride) Tablets Online
Available at: EZ Chemist Online Pharmacy (Insert live link when listed)
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