Imigran Migraine (Sumatriptan) 50mg Tablets
Imigran 50mg Tablets contain sumatriptan, a serotonin (5-HT1) receptor agonist used to treat acute migraine attacks. It works by narrowing blood vessels in the brain and reducing inflammatory substances, helping to relieve migraine symptoms such as headache, nausea, and sensitivity to light

Generic Name: Sumatriptan Succinate

Strength: 50mg

Form: Oral Tablets

Pack Size: 2 Tablets

Manufacturer: GlaxoSmithKline (GSK)

Drug Class: Serotonin (5-HT1) receptor agonist (Triptan)

Availability: Schedule 4 – Prescriptions Only Medicine (Australia)

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Sumatriptan (as succinate) 50mg per Tablet

Other Popular and Common Names
Sumatriptan

Triptan migraine Tablets

5-HT1 receptor agonists

Migraine abortive medication

Imigran 50mg oral Tablets

Sumavel (U.S. brand), Imitrex (U.S. brand)

Imigran contains sumatriptan, a selective serotonin (5-HT1B/1D) receptor agonist that acts on cranial blood vessels. During a migraine attack, blood vessels in the brain become dilated and inflamed. Sumatriptan works by:

Narrowing dilated cerebral blood vessels

Inhibiting the release of neuropeptides that cause pain and inflammation

Blocking pain signals in the brainstem

This mechanism rapidly relieves migraine symptoms such as headache, nausea, photophobia, and phonophobia without sedation.

Imigran 50mg is used for the acute treatment of:

Migraine headaches with or without aura

Cluster headaches (off-label with specialist advice)

Symptoms typically relieved include:

Moderate to severe headache pain

Nausea or vomiting

Sensitivity to light (photophobia)

Sensitivity to sound (phonophobia)

Note: Imigran is not intended for migraine prevention.

Adults (18 to 65 Years):
Initial Dose: 1 Tablet (50mg) taken as soon as migraine symptoms appear

Repeat Dose: If symptoms return, a second Tablet may be taken after 2 hours

Maximum Daily Dose: 2 Tablets (100mg) in 24 hours

Swallow Tablet whole with water

Can be taken with or without food

Children under 18 years

Adults over 65 years

Patients with uncontrolled hypertension, cardiovascular disease, or a history of stroke

Prescribing and Product Information
Prescriptions Required: Yes (Schedule 4 – Australia)

Onset of Action: Typically within 30–60 minutes

Duration: Relief can last up to 24 hours

Tablet Formulation: Immediate-release, film-coated

Safety Information
Common Side Effects:
Tingling or numbness

Flushing

Heaviness or pressure in the chest or limbs

Dizziness or drowsiness

Nausea

Serious Side Effects (Seek Immediate Medical Help):
Chest pain or palpitations

Shortness of breath

Severe stomach pain

Changes in vision

Signs of stroke (sudden weakness, slurred speech)

Do not use if allergic to sumatriptan or other triptans

Avoid in individuals with:

Ischaemic heart disease

History of stroke or TIA

Uncontrolled hypertension

Peripheral vascular disease

Do not use within 24 hours of taking:

Another triptan or ergotamine medication

MAO inhibitors (must wait at least 2 weeks)

Pregnancy and Breastfeeding:

Use only if benefits outweigh risks; consult your doctor

Avoid breastfeeding for 12 hours after taking a dose
Potential Interactions Include:
MAO inhibitors (e.g., phenelzine) – increased sumatriptan levels

SSRIs/SNRIs (e.g., fluoxetine, venlafaxine) – risk of serotonin syndrome

Ergotamine and other triptans – vasospasm risk

St John’s Wort – may increase serotonin toxicity risk

Backed by Clinical Evidence:
Sumatriptan in Acute Migraine – Cochrane Review

Efficacy of Sumatriptan – Randomized Controlled Trials (PubMed)

Pharmacological Class: Serotonin (5-HT1B/1D) Receptor Agonist

ATC Code: N02CC01

Schedule: S4 – Prescriptions Only Medicine (Australia)

Frequently Asked Questions (FAQ)
Q1: What is Imigran used for?
A: Imigran is used for the acute relief of migraine attacks, helping relieve headache, nausea, and light/sound sensitivity.

Q2: How quickly does Imigran 50mg work?
A: Relief generally begins within 30 to 60 minutes after taking a Tablet.

Q3: Can I take Imigran to prevent migraines?
A: No, it is not intended for prevention. It treats active migraine symptoms only.

Q4: Can I take a second dose if the migraine returns?
A: Yes, but wait at least 2 hours before taking a second Tablet. Do not exceed 2 Tablets in 24 hours.

Q5: Is Imigran safe during pregnancy or breastfeeding?
A: Only under medical supervision. Avoid breastfeeding for 12 hours after use.

Q6: Can I take Imigran with other painkillers?
A: You may take paracetamol or NSAIDs if advised, but do not take with other triptans or ergotamine-containing medications.

Genuine GSK product with full TGA approval

Effective prescription migraine relief with proven results

Fast, secure delivery across Australia

Professional pharmacist support and guidance

Trusted by migraine sufferers nationwide
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