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Austrialia
Inlife Evening Primrose Oil (EPO) 500 mg – 60 Capsules
Cold-pressed oil derived from Oenothera biennis seeds, standardized for 500 mg per vegetarian capsule. Rich in gamma-linolenic acid (GLA), an omega-6 fatty acid. Formulated to support skin hydration, hormonal balance, women’s health, joint comfort, heart health, and immune function. Manufactured in GMP, FSSAI, ISO-certified facilities.
Evening Primrose Oil (EPO) – also known as fever plant, king's cure-all, or sun drop.
Key bioactive component: GLA (8–10%), an essential omega-6, precursor to anti-inflammatory prostaglandin E1
Mode of Action
Anti-inflammatory effects: GLA converts to DGLA, reducing leukotriene formation and boosting PGE1 synthesis
Skin barrier support: Enhances moisture retention and reduces transepidermal water loss .
Hormonal balance: May alleviate PMS symptoms and cyclical breast discomfort through prostaglandin modulation
Cardiovascular and metabolic support: May improve lipid profiles, support blood pressure control, and aid insulin sensitivity
Uses & Benefits
Eczema & skin health: Enhances hydration and may reduce symptoms in mild atopic dermatitis
Acne & dryness from isotretinoin: Small studies indicate improved skin moisture and reduced irritation
PMS and mastalgia relief: Can reduce breast swelling, pain, and mood-related symptoms .
Menopausal support: May alleviate hot flashes and night sweats, though evidence remains limited
Joint support: May help with rheumatoid arthritis symptoms, though more data needed .
Cardiometabolic benefits: Potential improvements in cholesterol levels and blood pressure .
Nervous system support: May reduce diabetic neuropathy pain and enhance nerve function
Dosage & Administration
Typical dose: 1–2 capsules daily with food (500 mg–1 g GLA equivalent).
Clinical trials have used up to 6 g/day; 1–2 g/day is adequate for general wellness
Safety & Side Effects
Generally well-tolerated; possible mild gastrointestinal upset, headache, and diarrhea
Reported episodes of nausea, altered taste, and bloating
.Rare case reports of seizures in individuals with epilepsy or on phenothiazines
Warnings & Cautions
Avoid during pregnancy or lactation—may affect labor and neonatal health .
Bleeding risk: May enhance effects of anticoagulants (e.g., warfarin, aspirin) or NSAIDs .
Seizure threshold: Use caution in epilepsy or psychosis, especially with phenothiazines .
Drug Classification & Interactions
Classified as an OTC herbal supplement.
Interacts with blood thinners, CYP3A4 substrates, phenothiazines, and anticonvulsants
Clinical & Consumer Insights
Eczema: Lacking conclusive improvement versus placebo in pooled trials .
Rheumatoid arthritis: Some trials (6 g/day) report reduced need for NSAIDs during treatment .
PMS symptoms: Up to 71% symptom relief noted in small Brazilian trial
Skin hydration: Improved in context of isotretinoin therapy and mild eczema
Frequently Asked Questions
Q: How long before I notice benefits?
A: Skin and PMS improvements may take 2–4 months; joint or metabolic effects could require similar duration.
Q: Safe for pregnant women?
A: No—may impact labor and neonatal bleeding. Avoid use during pregnancy/lactation
Q: Will it thin blood?
A: EPO may enhance anticoagulant and NSAID effects; monitor closely if you are on such medications
Q: Can I take it for eczema?
A: Evidence is mixed; some see benefit in moisture and inflammation but meta-analyses do not confirm consistent efficacy
Q: Is it safe with other meds?
A: Caution advised if taking anticoagulants, liver-metabolized drugs, anticonvulsants, antipsychotics, or immune modulators .
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