Maxalt Migraine Relief 5 mg Wafer – 2-Pack
Fast-acting migraine treatment for adults and children (6+ years)

Maxalt 5 mg wafer (rizatriptan) is a fast-dissolving serotonin (5‑HT₁B/1D) receptor agonist that inhibits migraine pain and relieves symptoms like nausea, light, and sound sensitivity; one 5 mg wafer at onset, may repeat once after 2 hours, max 30 mg/day.

Brand/Product Name: Maxalt Migraine Relief Wafer

Generic Name: Rizatriptan benzoate 5 mg

Dosage Form: Orally dissolving wafer

Pack Size: 2 wafers

Drug Class: Triptan (5‑HT₁B/1D receptor agonist)

Availability: Prescriptions-only

Purchase at: EZ Chemist Online Pharmacy

Rizatriptan benzoate 5 mg

Also known as: Rizatriptan ODT, Maxalt‑MLT, RizaFil

Rizatriptan targets 5‑HT₁B/1D receptors, causing vasoconstriction of intracranial blood vessels and inhibiting neuropeptide (CGRP) release to interrupt migraine pathways

Acute treatment of migraine with or without aura in adults and children ≥ 6 years
Adults (≥ 18 years):

5 mg wafer at migraine onset.

May repeat once after ≥ 2 hours if needed.

Max 30 mg/day (6 wafers)

Children 6–17 yrs:

< 40 kg: 5 mg once daily.

≥ 40 kg: 10 mg once (wafer form should be modified per prescription)

With propranolol:

Adults: Max 5 mg per dose, ≤ 3 doses/day (15 mg/day).

Children ≥ 40 kg: Single 5 mg dose only

Administration:

Place wafer on tongue; allows it to dissolve; take on empty or full stomach
Safety & Side Effects
Common (≥ 2%):

Dizziness, fatigue, dry mouth, somnolence, paresthesia, nausea

Chest/throat tightness, serotonin syndrome, cardiovascular events (e.g., heart attack, stroke), hypersensitivity .

Warnings & Precautions
Contraindicated: cardiovascular disease, uncontrolled hypertension, ischemic bowel, hemiplegic/basilar migraine, MAO inhibitors (within 14 days), ergot alkaloids (within 24 h)

Not recommended for frequent use (>4 migraines/month or >10 days/month) .

Pregnancy and breastfeeding: use only if benefits outweigh risks; avoid within 24 hours before breastfeeding .

Propranolol: increases rizatriptan levels; dosing limited (see dosage section)

SSRIs/SNRIs/TCAs/MAOIs: risk of serotonin syndrome; monitor if co-administered

Ergots/other triptans: contraindicated within 24 hours

CYP450 2D6: minimal effect; no monitoring usually needed

Oral contraceptives & paroxetine: no significant interaction observed

Drug Classification
Pharmacologic Class: 5‑HT₁B/1D agonist (triptan)

Therapeutic Class: Antimigraine agent

Legal Status: Prescriptions-only (S4)

Frequently Asked Questions (FAQ)
Q1. When should I take the wafer?
Take at the first sign of migraine for best effect.

Q2. Can I take a second wafer?
Yes, but only ≥ 2 hours after the first and do not exceed 30 mg/day.

Q3. Is it suitable for children?
Yes, children ≥ 6 years with weight-based dosing; consult a doctor.

Q4. Can I take it with propranolol?
Yes, but limit to 5 mg doses and ≤ 3 doses/day in adults, single 5 mg in children ≥ 40 kg.

Q5. Can I use it during pregnancy?
Use only if prescribed; avoid during breastfeeding for 24 hours after dose.

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