Nicotinell Patch 21 mg – 28 Patches
Step‑1 Nicotine transdermal patch providing steady 24-hour nicotine delivery

Nicotine 21 mg/day (52.5 mg in patch, releases 21 mg/24 h) via transdermal delivery system

Nicotine patch, transdermal nicotine system, Nicotinell TTS 21.

Nicotine Replacement Therapy (NRT) — non-prescription, pharmacy-only OTC aid for tobacco dependence

Delivers a consistent daily dose of nicotine through the skin to reduce cravings and withdrawal by replacing smoking-induced spikes
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Aids adult smokers seeking to stop or reduce smoking.

Initial strength for those who smoke >10 cigarettes/day or experience early cravings
Apply one patch daily to clean, dry, non-hairy skin (upper arm, chest, shoulder, or back)

Press firmly for 10 seconds; rotate application sites daily to prevent skin irritation

Worn for 16–24 hours (remove at bedtime if vivid dreams occur)

Weeks 1–4: 21 mg patch

Weeks 5–8: 14 mg patch

Weeks 9–12: 7 mg patch — follow up with posts 1–3 as per program

Skin irritation/redness, headache, nausea, dizziness, insomnia, vivid dreams

Palpitations, chest pain, hypertension, allergic reactions, mood changes .

Not for non-smokers, nicotine-naïve individuals, or children under 18 (unless medical advice) .

Consult a doctor if you have heart disease, recent MI, arrhythmias, uncontrolled hypertension, stroke, or skin disorders .

Caution during pregnancy or breastfeeding—NRT is safer than smoking but requires medical guidance

Nicotine may interact with acetaminophen, caffeine, insulin, beta-blockers (e.g., propranolol), theophylline, imipramine, furosemide, adenosine

Quitting smoking may affect drug metabolism; monitor medications like warfarin, theophylline, antipsychotics, caffeine .

Feature Specification
Generic name Nicotine transdermal patch 21 mg/24 h
Form Transdermal patch, Step 1 strength
Class Nicotine Replacement Therapy (NRT)
Status OTC, pharmacy-only

Frequently Asked Questions
Q1. Who should use the 21 mg patch?
A1. Recommended for smokers of over 10 cigarettes/day, or those who smoke early after waking

Q2. When should I remove the patch?
A2. Typically after 24 hours; remove before bedtime if vivid dreams or insomnia occur .

Q3. Can I combine with gum or lozenges?
A3. Yes, using gum or lozenges for breakthrough cravings enhances efficacy .

Q4. What if skin irritation persists?
A4. Rotate skin sites daily; persistent irritation may require patch-free days or doctor consultation.

Q5. Can I use for more than three months?
A5. Beyond 6 months requires medical advice. Step-down program typically lasts 8–12 weeks .

What is Nicotinell 21 mg nicotine patch used for?
Nicotinell 21 mg patch provides controlled nicotine delivery for heavy smokers (>10 cigarettes/day), reducing withdrawal and cravings. Apply a new patch each morning for 4 weeks, then step down through 14 mg and 7 mg patches over 12 weeks to support successful smoking cessation.

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