Nurofen 400 mg – 12 Tablets
Maximum Strength Ibuprofen Fast Pain & Inflammation Relief

Ibuprofen 400 mg per Tablet – a potent nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, and antipyretic properties

Ibuprofen 400 mg Tablets

Also marketed under names such as Nurofen Double Strength, Advil, Motrin, Brufen

Non-selective NSAID (nonsteroidal anti-inflammatory drug)

Ibuprofen inhibits COX‑1 and COX‑2 enzymes, reducing prostaglandin synthesis to decrease pain, inflammation, and fever

Acute pain (e.g., headache, toothache, migraine, period pain, back and muscle aches)

Inflammatory conditions (e.g., osteoarthritis, rheumatoid arthritis flares)

Fever reduction associated with cold, flu, and infections

Adults and adolescents ≥12 years:

Single dose: 1 Tablet (400 mg) every 4–6 hours as needed

Max OTC dose: 3 Tablets (1 200 mg/day); higher doses (up to 3 200 mg/day) only under medical supervision
nhs.uk


Swallow whole with water or milk before or after meals to minimize stomach upset

Each pack contains 12 coated Tablets

Store at room temperature (<25 °C), away from children

Indigestion, heartburn, nausea, headache, dizziness, rash

Gastrointestinal bleeding, ulceration, kidney impairment, elevated liver enzymes

Cardiovascular risks: myocardial infarction, stroke with prolonged/high-dose use

Hives, facial swelling, breathing difficulty; anaphylaxis or serious skin reactions (SJS/TEN)

Avoid overuse—risk of GI bleeding, heart, liver, and kidney damage

Risk factors: age >60, prior ulcers, concurrent corticosteroid or anticoagulant use

Contraindicated in aspirin/NSAID allergy, active GI bleeding, Crohn’s, heart failure, severe kidney/liver disease

Pregnancy: avoid after 20 weeks; increases fetal risks

May cause dizziness—avoid driving or operating machinery if affected

Anticoagulants: elevated bleeding risk

ACE inhibitors, diuretics: reduced kidney function

Lithium, methotrexate: increased toxicity risk

Avoid combo with other NSAIDs and excessive alcohol

FAQ (Q&A)
Q1. How fast is relief?
A1. Pain relief typically starts within 30–60 minutes

Q2. Can I take it twice daily?
A2. Yes—400 mg every 4–6 hours, max 1 200 mg OTC; higher doses require medical guidance

Q3. Can I mix with paracetamol?
A3. Yes, combining can enhance pain relief; they have different mechanisms and no interaction

Q4. Is it safe for arthritis?
A4. Effective for short-term use; long-term use may require gastric protection (e.g., PPIs)

Q5. Can pregnant women use it?
A5. Avoid after 20 weeks; early pregnancy use only if necessary under medical advice

What is Nurofen 400 mg used for?
Nurofen 400 mg Tablets provide fast and effective relief from mild‑to‑moderate pain—such as headaches, menstrual cramps, toothaches, muscle and back pain—along with fever and inflammation. One Tablet every 4–6 hours, up to three per day.

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