Comprehensive Product Description Guide: Avelox (Moxifloxacin Hydrochloride)
Paired Product Reference: Blackmores Conceive Well Gold 28 Tablets + 28 Capsules
Avelox antibiotic, moxifloxacin 400 mg tablets, respiratory infection treatment, fluoroquinolone antibiotic, EZ Chemist Avelox
Avelox (moxifloxacin) is a broad-spectrum fluoroquinolone antibiotic used to treat serious respiratory, skin, intra-abdominal, and pelvic infections. It works by inhibiting bacterial DNA replication enzymes.
Brand Name: Avelox

Generic Name: Moxifloxacin Hydrochloride

Form & Strength: 400 mg film-coated tablets (also available as IV formulation)
Drug Class: Fluoroquinolone antibiotic (fourth-generation)
Schedule: Prescription only (Schedule 4 in Australia)
Moxifloxacin Hydrochloride 400 mg — a bactericidal agent that inhibits DNA gyrase and topoisomerase IV, preventing DNA replication
Moxifloxacin

Moxifloxacin Systemic

Avalox (alternate brand)

IV formulation also marketed as Avelox I.V.
DailyMed
Avelox targets DNA gyrase and topoisomerase IV, enzymes essential for bacterial DNA synthesis. This prevents bacterial replication, resulting in bacterial cell death (bactericidal effect)
Mayo Clinic
Acute exacerbations of chronic bronchitis and community-acquired pneumonia (CAP)
Acute bacterial sinusitis

Uncomplicated skin and skin structure infections

Pelvic inflammatory disease (PID)
Cleveland Clinic
Complicated skin and intra-abdominal infections

IV to oral switch therapy possible without dose change
Dosage & Administration
Adults: 400 mg once daily, with or without food
University of Rochester Medical Center
IV Infusion: 60-minute infusion for inpatients, followed potentially by oral transition

Treatment Duration: 5–21 days depending on infection type; follow specific clinical guidelines

No dosage adjustment needed in renal or mild–moderate hepatic impairment
DailyMed
Prescription-only; not recommended for children (<18 years)

Baseline and periodic monitoring:

Electrolytes, liver function, ECG if at risk of QT prolongation

Signs of tendonitis, neuropathy, psychiatric or CNS symptoms
Nausea, diarrhea, headache, dizziness
Healthline
Mild CNS effects: insomnia, restlessness
Tendonitis/tendon rupture, especially in older adults and corticosteroid users
Healthline

Peripheral neuropathy — may persist after discontinuation
Medsafe
QT prolongation/arrhythmias — avoid with Class IA/III antiarrhythmics
FDA Access Data

Psychiatric effects: agitation, hallucinations, suicidal thoughts

Hypoglycemia or hyperglycemia — risk increased in diabetic patients

Photosensitivity — heightened skin sensitivity to UV light
Medsafe
Clostridioides difficile–associated diarrhea — can be severe
Not recommended in children or during pregnancy/breastfeeding due to musculoskeletal toxicity concerns

Avoid use in patients with myasthenia gravis — may exacerbate muscle weakness

Avoid sunlamps/UV exposure; sun protection advised
Cleveland Clinic
Discontinue at first sign of neuropathy or psychiatric symptoms
Avoid concurrent steroids to reduce tendon rupture risk
European Medicines Agency (EMA)

Antacids, scralfate, iron, calcium, zinc — reduce absorption; dose separately by 4–8 hours
Class IA/III antiarrhythmics — additive QTc prolongation; avoid concomitant use
FDA Access Data

Warfarin — may increase INR; monitor clotting times

Corticosteroids, NSAIDs — raise risk of tendonitis, seizures

Hypoglycemic agents — may amplify blood sugar fluctuations; diabetic monitoring advised

Contraceptives, Blackmores Conceive Well Gold — no interaction concerns, but antibiotic therapy may temporarily reduce contraceptive efficacy
ATC Code: J01MA14

Pharmacologic Class: Fluoroquinolone antibiotic

Therapeutic Class: Antibacterial

Schedule 4 (Prescription only)

Not indicated for pediatric use <18 years

Frequently Asked Questions (FAQs)
Q1. Can I drive while taking Avelox?
A: It can cause dizziness, drowsiness, or visual disturbances—avoid driving or operating machinery until effects are known

Q2. Can I take antacids with Avelox?
A: Yes, but separate dose by at least 4 hours before or 8 hours after taking Avelox
University of Rochester Medical Center
Q3. Is Avelox safe during pregnancy?
A: Use only if essential; animal data suggests risk, so pregnancy must be confirmed before prescription .

Q4. What should I do if I experience tendon pain?
A: Discontinue immediately and seek medical attention. Avoid physical strain on affected tendons .

Q5. How long is Avelox treatment?
A: Duration depends on the infection—5 days for sinusitis, 7–14 days for pneumonia, up to 21 days for complicated infections .
Included in international treatment guidelines for community-acquired pneumonia and complicated skin infections
MIMS

Demonstrated non-inferior efficacy compared to older fluoroquinolones, with the convenience of once-daily dosing

Listed on the World Health Organization Essential Medicines List
Store between 15–30 °C in original container

Keep away from moisture and light

Store tablets at room temperature, avoid bathrooms
Keep out of reach of children and pets
Avelox, moxifloxacin 400 mg, fluoroquinolone antibiotic, respiratory & skin infections, once-daily oral, Rx only, EZ Chemist