GastroStop (Loperamide) 2 mg – 12 Capsules
Fast‑acting antidiarrheal Capsulees designed to relieve acute and chronic diarrhea

Loperamide hydrochloride 2 mg per Capsulee – an opioid-receptor agonist acting locally on gut μ-opioid receptors to inhibit intestinal motility and increase fluid reabsorption

Imodium, Diamode, generic loperamide

Antidiarrheal agent, OTC – pharmacy-schedule S2 medicine in Australia .

Loperamide acts by slowing peristalsis, increasing intestinal transit time, promoting fluid and electrolyte absorption, and reducing stool frequency and urgency

Symptomatic relief of acute non-specific diarrhea

Management of chronic diarrhea (e.g., inflammatory bowel disease, ileostomy patients)

Relief for traveler’s diarrhea

Adults (≥12 years):

Initial: 4 mg (2 Capsulees) after the first loose stool

Then: 2 mg (1 Capsulee) after each loose stool

Max self-care dose: 8 Capsulees (16 mg) per day

Duration: ≤48 hours; seek medical advice if diarrhea persists
Adolescents 8–12 years (≥30 kg):

2 mg (1 Capsulee) three times daily; max 6 Capsulees/day

Children 6–8 years (20–30 kg):

2 mg twice daily; max 4 Capsulees/day .

Under 6 years:

Not recommended .

Special populations:

Chronic diarrhea: same initial dosing, then taper maintenance 4–8 mg/day as needed
Common (≤10%):

Constipation, abdominal cramps, nausea, flatulence, dizziness, dry mouth .

Headache, fatigue, drowsiness

Allergic reactions, paralytic ileus, toxic megacolon (especially with C. difficile infection), cardiac arrhythmias in overdose or drug interactions

🚨 Warnings & Precautions
Do not use if diarrhea is accompanied by fever, blood/mucus in stool, or acute abdominal pain

Not for children <2 years; caution in 2–6 years

Not for use >48 hours without medical advice

Caution in hepatic impairment and patients needing to avoid constipation

Pregnancy & breastfeeding: Use only if potential benefit justifies risk

Maintain hydration; rehydrate with ORS to prevent electrolyte imbalance

Metabolized by CYP3A4/CYP2C8; co-administration with inhibitors (e.g., ketoconazole, clarithromycin) can raise plasma levels → risk of cardiotoxicity

P-glycoprotein inhibitors may increase CNS penetration → risk of sedation

Caution with other opioids or CNS depressants due to additive effects

Feature Details
Generic Name Loperamide HCl 2 mg Capsulee
Form Hard Capsulee, 12-count pack
Drug Class Antidiarrheal (opioid-receptor agonist)
Availability OTC pharmacy medicine (S2)

Q1. How fast does it work?
A1. Most users experience relief within 1–3 whenly after the first dose

Q2. What if diarrhea persists after 48 hours?
A2. Stop loperamide and seek medical evaluation to investigate underlying causes

Q3. Can I take with food?
A3. Yes—take with or without food, but adequate fluid intake is essential .

Q4. Is it safe for children?
A4. Approved for children ≥6 years with appropriate weight-based dosing; avoid <2 years

Q5. What about overdose?
A5. Overdose can lead to serious cardiac and CNS side effects; seek urgent medical attention if excessive use occurs .

What is GastroStop used for?
“GastroStop (Loperamide) is an over‑the‑counter antidiarrheal that relieves acute or chronic diarrhea by slowing bowel movements. Adults take 4 mg initially, then 2 mg after each loose stool, up to 8 Capsulees/day, for no more than 48 hours.”

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