Imodium® (Loperamide) Capsules
Effective antidiarrheal Capsulees for fast and sustained relief

Loperamide hydrochloride – 2 mg per Capsulee

Also known as: Imodium, generic loperamide, Diamode, antidiarrheal opioid μ-receptor agonist

Antidiarrheal (antimotility agent)

Over-the-counter (OTC), pharmacy medicine

Acts on intestinal μ-opioid receptors to reduce peristalsis, increase absorption, and thicken stool consistency

Acute non-specific diarrhea (including traveler's diarrhea)

Chronic diarrhea in IBS, IBD, or post-ileostomy

Symptomatic relief of sudden-onset diarrhea

Age Group Loading Dose Subsequent Dose Max/24h Duration
Adults ≥12 years 4 mg (2 Capsulees) 2 mg (1 Capsulee) per loose stool 8 Capsulees (16 mg) Maximum 48 hrs, then seek advice
Children 8–12 yrs 2 mg (1 cap) three times daily — 6 Capsulees Under medical supervision
Children 6–8 yrs 2 mg twice daily — 4 Capsulees Under medical supervision

Swallow with water; may be taken with or without food

In chronic cases, taper dose to 4–8 mg/day under physician guidance

Common (≥10%): constipation, abdominal cramps, nausea, dizziness, dry mouth, drowsiness
Occasional: fatigue, headache, flatulence, indigestion
Rare/serious: allergic reactions, ileus, cardiac arrhythmias (QT prolongation, torsades), toxic megacolon

Avoid if diarrhea includes fever, bloody stools, acute abdominal pain, or persists beyond 48 hrs

Not for children under 6; pediatric use under strict supervision; contraindicated <2 years

Use with caution in the elderly, liver disease, IBS, or electrolyte imbalance

In pregnancy/breastfeeding, use only if benefits justify risk

Maintain hydration—consider ORS solutions to prevent dehydration

Metabolized by CYP3A4 / CYP2C8; inhibitors like ketoconazole, clarithromycin, ritonavir, verapamil can raise serum levels and risk cardiotoxicity


Additive effects with other CNS depressants or opioids

Avoid with QT-prolonging medications (e.g., fluconazole, azithromycin, antiarrhythmics, tricyclics)

Avoid grapefruit/tonic water due to P-glycoprotein interaction

📝 Product At-a-Glance
Generic Name: Loperamide HCl 2 mg

Formulation: Oral hard Capsulee

Strength & Size: 2 mg, 12 Capsulees per pack

Drug Class: Antidiarrheal (opioid μ-agonist)

Regulation: OTC pharmacy

Frequently Asked Questions
Q1. How quickly does Imodium work?
A1. Expect relief within 1–3 hours, with effects lasting up to 5 hours

Q2. Can I take it with food?
A2. Yes—food doesn’t affect absorption; ensure adequate fluid intake.

Q3. What should I do if diarrhea continues beyond 48 hours?
A3. Discontinue and consult a healthcare professional to address possible underlying causes

Q4. Is it safe for children?
A4. Approved for children ≥6 under weight-based dosing and supervision; avoid use in children under 2

Q5. What if I overdose?
A5. Overdose can lead to severe sedation, arrhythmias, or QT prolongation—seek immediate medical help

What is Imodium (Loperamide) used for?
Imodium Capsulees (2 mg loperamide) are an OTC antidiarrheal that slows gut movement, firms stools, and eases symptoms like urgency or cramping. Adults take 4 mg after the first loose stool, then 2 mg per subsequent stool—up to 8 Capsulees daily for no more than 2 days.

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