Forzest (Tadalafil) – Long-Acting Erectile Dysfunction Treatment

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What is Forzest used for
Forzest is a prescription medication that contains tadalafil, used to treat erectile dysfunction (ED) in adult men. It enhances blood flow to the penis during sexual stimulation, helping men achieve and maintain a firm erection.

Brand Name: Forzest

Generic Name: Tadalafil

Strength Available: 20 mg

Drug Class: Phosphodiesterase-5 (PDE5) Inhibitor

Formulation: Oral tablet

Manufacturer: Ranbaxy Laboratories (a Sun Pharma company)

Prescription Required: Yes

Administration Route: Oral

Legal Classification: Prescription Only Medicine (POM)

Buy Forzest 20 mg Tablets – EZ Chemist
Tadalafil 20 mg per tablet. Tadalafil is a long-acting PDE5 inhibitor that increases blood flow to the penis by relaxing penile blood vessels during sexual arousal.

Generic Cialis

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ED Medication

PDE5 Inhibitor

Tadalafil works by selectively inhibiting phosphodiesterase type 5 (PDE5), the enzyme responsible for degrading cyclic guanosine monophosphate (cGMP) in the corpus cavernosum.

During sexual arousal, nitric oxide (NO) is released.

NO stimulates cGMP, leading to smooth muscle relaxation.

Increased blood flow results in an erection.

Tadalafil prolongs cGMP activity, allowing for enhanced erectile function.

Onset of action: 30–60 minutes
Duration of action: Up to 36 hours

Forzest is prescribed for:

Erectile Dysfunction (ED) in adult males

Benign Prostatic Hyperplasia (BPH) (off-label or alternate brands)
Standard Dosage for ED:

Use Type Dosage Timing
On-Demand 10–20 mg 30–60 minutes before intercourse
Not for Daily Use Do not take more than once per 24 hours

Sexual stimulation is required for the medication to work.

Can be taken with or without food.

Avoid alcohol and grapefruit juice.

Initial recommended dose: 10 mg

May be increased to 20 mg or decreased to 5 mg based on individual response

Not intended for use in women or adolescents

Use with caution in patients with cardiovascular risk

Not indicated for females or children under 18

Caution in men with liver or kidney impairment

Avoid in combination with nitrates or riociguat

Not to be used more than once daily

Special Considerations:

Avoid in severe hepatic impairment

Dose adjustment required in renal insufficiency

Monitor blood pressure in patients on antihypertensive therapy

Common Adverse Effects:

Headache

Back pain

Dyspepsia

Nasal congestion

Myalgia

Flushing

Serious Adverse Effects (Rare):

Priapism (prolonged erection)

Sudden vision loss (NAION)

Sudden hearing decrease or loss

Cardiovascular events in predisposed individuals

Seek immediate medical attention if erection lasts more than 4 hours or if sudden loss of vision or hearing occurs.

Cardiac Risk: Avoid in patients with recent heart attack or stroke

Priapism Risk: Use cautiously in patients with anatomical penis deformity

Drug Interactions: Strictly avoid nitrates and certain antifungal or antiviral drugs

Alcohol: Can increase risk of hypotension

Driving: May cause dizziness or visual disturbances

Drug Class / Agent Interaction
Nitrates Severe hypotension – contraindicated
Alpha-blockers Risk of symptomatic hypotension
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) Increased Tadalafil levels
Antihypertensives Enhanced blood pressure-lowering effect
Grapefruit Juice May affect drug metabolism – avoid

Metabolism: Hepatic via CYP3A4 enzyme system

ATC Code: G04BE08

Schedule: Schedule H (Prescription only in India)

Therapeutic Class: Erectile Dysfunction Treatment

Legal Status: Prescription Drug

Clinical Studies and Evidenc
Montorsi F. et al. (2004) – Tadalafil significantly improved International Index of Erectile Function (IIEF) scores in men with ED.

Porst H. et al. (2001) – Demonstrated high efficacy of tadalafil over placebo in large-scale Phase III trials.

FDA & EMA Approved: Tadalafil is globally approved for ED and BPH.

Frequently Asked Questions (FAQs)
Q1. What is Forzest used for?
Forzest is used to treat erectile dysfunction by increasing blood flow to the penis, improving sexual performance.

Q2. How long does Forzest last?
Forzest (Tadalafil) can remain effective for up to 36 hours, earning it the nickname “weekend pill.”

Q3. Can I take Forzest daily?
No, Forzest is meant for on-demand use only. For daily therapy, a lower-dose tadalafil (2.5–5 mg) may be prescribed under different brands.

Q4. Is Forzest the same as Cialis?
Yes, both contain the same active ingredient (Tadalafil). Forzest is an Indian-manufactured generic.

Q5. What happens if I take alcohol with Forzest?
Alcohol may lower blood pressure and increase the risk of side effects like dizziness or fainting.

Q6. Does Forzest protect against STDs?
No, Forzest does not prevent sexually transmitted infections. Use appropriate protection if needed.

Store at temperatures below 30°C

Keep away from moisture and direct sunlight

Keep out of reach of children

Do not use expired tablets

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