Comprehensive Product Description Guide: Generic Cialis (Tadalafil)

What is Generic Cialis (Tadalafil) used for
Generic Cialis contains tadalafil, a PDE5 inhibitor used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH) in men. It enhances blood flow to specific areas of the body, particularly the penis, enabling a natural response to sexual stimulation.

Generic Cialis
Active Ingredient: Tadalafil
Brand Equivalent: Cialis (Original by Eli Lilly)
Available Strengths: 2.5 mg, 5 mg, 10 mg, 20 mg tablets
Packaging: Blister packs of 2, 4, 8, or 20 tablets

Tadalafil tablets

Weekend Pill

Generic Tadalafil

PDE5 inhibitor tablets
Tadalafil – a selective phosphodiesterase type 5 (PDE5) inhibitor

Drug Class: Erectile Dysfunction Treatment

Regulatory Status: Prescription-only medicine in Australia (Schedule 4)

Mode of Action
Tadalafil works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), responsible for the breakdown of cyclic guanosine monophosphate (cGMP). Increased cGMP levels allow relaxation of smooth muscles and vasodilation in the penis, improving blood flow and facilitating an erection during sexual stimulation. It is not an aphrodisiac and requires sexual arousal to work.

Generic Cialis (Tadalafil) is used for:

Erectile Dysfunction (ED) – improves the ability to attain and maintain an erection

Benign Prostatic Hyperplasia (BPH) – alleviates urinary symptoms such as urgency, hesitancy, and weak stream

ED with BPH – dual action for men with both conditions

Erectile Dysfunction (On-Demand Use):
10 mg to 20 mg taken at least 30–60 minutes before sexual activity. Maximum once daily.

Erectile Dysfunction (Daily Use):
2.5 mg to 5 mg once daily, at the same time each day, regardless of sexual activity.

Benign Prostatic Hyperplasia:
5 mg once daily

With or without food

Note: Always follow prescribing doctor’s instructions for dosage based on condition, age, and tolerance.

Start with the lowest effective dose

Adjust based on response and tolerability

Do not exceed one dose in 24 hours

Not suitable for use in women or children

Safety Information:
Use with caution in cardiovascular disease

Avoid in cases of severe liver or kidney impairment

Not for use with nitrate-containing drugs (risk of hypotension)

Avoid grapefruit or grapefruit juice – may increase tadalafil levels

Common:

Headache

Flushing

Indigestion

Back pain

Nasal congestion

Muscle aches

Less Common but Serious:

Sudden vision loss (rare, related to NAION)

Hearing loss

Priapism (prolonged erection >4 hours)

Seek medical attention if side effects are severe or persistent.
Cardiovascular Risk: Not recommended for men advised against sexual activity

Liver/Kidney Disease: Dose adjustments required

Priapism Risk: Use cautiously in men with anatomical deformities of the penis or predisposing conditions

Drug Interactions: Avoid with strong CYP3A4 inhibitors or nitrates
Contraindicated with Nitrates: (e.g., nitroglycerin, isosorbide dinitrate)

Caution with:

Alpha-blockers (e.g., tamsulosin)

Antihypertensives

Antifungals (ketoconazole, itraconazole)

HIV protease inhibitors

Antibiotics like erythromycin

Grapefruit juice (CYP3A4 interaction)

Clinical Note: Co-administration with nitrates can cause life-threatening hypotension.
Erectile Dysfunction Study (NEJM, 2003): Tadalafil improved erectile function in 81% of patients vs 35% with placebo

BPH Studies (Eur Urol, 2011): 5 mg tadalafil daily significantly reduced urinary symptoms and improved quality of life

Long Duration: Tadalafil is effective for up to 36 hours post-dose

Frequently Asked Questions (FAQs)
Q: What is the difference between Cialis and Generic Cialis?
A: Both contain tadalafil and are equally effective. Generic versions are more cost-effective.

Q: How long does Generic Cialis take to work?
A: It starts working within 30 to 60 minutes, with effects lasting up to 36 hours.

Q: Can I take it every day?
A: Yes, at lower doses (2.5 mg or 5 mg), tadalafil can be used daily. Consult your doctor.

Q: Is it safe with alcohol?
A: Moderate alcohol is usually safe, but excessive alcohol may increase side effects or lower blood pressure.

Q: Can I use it with blood pressure medication?
A: Yes, but caution is advised. Avoid nitrates and certain alpha-blockers.
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