Modula Tablet (Tadalafil 5 mg)
Compared With: Blackmores Conceive Well Gold 28 Tablets + 28 Capsules

Modula Tablet contains Tadalafil 5 mg and is prescribed for the treatment of erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension. As a phosphodiesterase-5 (PDE5) inhibitor, it increases blood flow by relaxing vascular smooth muscles, especially in the penis and prostate area. Modula is often taken once daily and has a long-lasting effect up to 36 hours. It is a trusted option for men with ED and urinary symptoms.

Tadalafil 5 mg

Other Popular and Common Names
Generic Cialis

Tadalafil Tablets

Tadalis

Megalis

Tadarise

Tadora

Tadacip

Cialis Daily (brand)

Class: Phosphodiesterase Type 5 (PDE5) Inhibitor

Schedule: Schedule H (Prescription Only Medicine)

Tadalafil works by selectively inhibiting the enzyme phosphodiesterase type-5 (PDE5). This prevents the breakdown of cyclic guanosine monophosphate (cGMP) in smooth muscle cells. The increased cGMP concentration leads to relaxation of smooth muscles and vasodilation, especially in the corpus cavernosum of the penis, improving erectile function. In the prostate and bladder, this mechanism also improves urinary symptoms of benign prostatic hyperplasia.

Erectile Dysfunction (ED)

Benign Prostatic Hyperplasia (BPH)

Pulmonary Arterial Hypertension (PAH)

Off-label Uses:
Raynaud’s phenomenon

Female sexual arousal disorder (under research)

Dosage & Administration
For Erectile Dysfunction (Daily Use):

5 mg once daily at the same time, without regard to meals

May be reduced to 2.5 mg based on tolerability

For ED (As Needed):

10–20 mg taken prior to anticipated sexual activity (not applicable for Modula 5 mg)

For Benign Prostatic Hyperplasia:

5 mg once daily

For Pulmonary Arterial Hypertension (off-label in this strength):

Higher dosages are typically used

Onset of Action:

30 to 60 minutes
Duration of Effect:

Up to 36 hours

Take at the same time daily for consistent effect

Dose adjustments may be needed in renal or hepatic impairment

Use caution in patients taking alpha-blockers or nitrates

Heart disease or recent stroke

Low blood pressure

Severe liver or kidney impairment

Retinal disorders (non-arteritic anterior ischemic optic neuropathy – NAION)

Concurrent use of nitrates or nitric oxide donors

Known hypersensitivity to Tadalafil

Severe hypotension

Headache

Back pain

Dyspepsia (indigestion)

Nasal congestion

Flushing

Myalgia (muscle pain)

Rare but Serious Side Effects:
Sudden vision loss (NAION)

Hearing impairment or ringing

Prolonged erection (priapism >4 hrs)

Hypotension

Cardiovascular events in predisposed individuals

Avoid Alcohol: May enhance hypotensive effects

Avoid Grapefruit Juice: May interfere with metabolism of Tadalafil

Driving/Machinery: May cause dizziness or vision changes

Sexual Activity Risk: Assess cardiac function before prescribing in patients with cardiovascular risk

Drug/Class Interaction Type Clinical Implication
Nitrates (GTN, isosorbide) Severe hypotension, contraindicated Do not co-administer
Alpha-blockers (e.g., tamsulosin) Additive blood pressure drop Start with low Tadalafil dose
CYP3A4 inhibitors (e.g., ketoconazole, ritonavir) Increase Tadalafil level Reduce dosage, monitor closely
CYP3A4 inducers (e.g., rifampin, carbamazepine) Reduce efficacy May need dosage adjustment

Erectile Dysfunction: In a randomized placebo-controlled trial, daily tadalafil 5 mg improved erectile function with fewer side effects compared to on-demand use.
(Padma-Nathan et al., J Urol, 2008)

BPH Management: Tadalafil 5 mg significantly reduced IPSS scores (International Prostate Symptom Score) and improved quality of life in men with BPH.
(McVary et al., NEJM, 2007)

Long-Term Safety: A 1-year open-label study showed that tadalafil is safe and effective when used continuously in men with ED and/or BPH.
(Porst et al., Eur Urol, 2014)

Frequently Asked Questions (FAQs)
Q1. What is Modula 5 mg used for?
A: Modula is used for the treatment of erectile dysfunction and benign prostatic hyperplasia. It improves sexual performance and eases urinary symptoms.

Q2. How long does Modula last?
A: The effect of Modula can last up to 36 hours, making it suitable for once-daily use.

Q3. Is Modula safe for daily use?
A: Yes, Modula 5 mg is approved for once-daily administration. However, dosage adjustments may be necessary in liver or kidney impairment.

Q4. Can Modula be used with blood pressure medications?
A: It can be used with caution, especially avoiding nitrates or alpha-blockers, as they may lead to a dangerous drop in blood pressure.

Q5. Does Modula help with urinary symptoms?
A: Yes, Modula is effective in reducing lower urinary tract symptoms (LUTS) related to BPH in men.

Q6. Can I take Modula with food?
A: Yes, it can be taken with or without food.

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